Includes bibliographical references and index

Review of renal physiology -- Regulation of salt and water balance -- Disorders of water balance: hyponatremia, hypernatremia, and polyuria -- Edematous states and the use of diuretics -- Acid-base physiology and metabolic alkalosis -- Metabolic acidosis -- Disorders of potassium balance -- Urinalysis and approach to the patient with renal disease -- Pathogenesis of major glomerular and vascular diseases -- Tubulointerstitial diseases -- Acute renal failure -- Progression of chronic renal failure -- Signs and symptoms of chronic renal failure

This text offers medical students a case-based approach to learning the mechanisms of renal disease. Each chapter covers a disease, beginning with a patient case and followed by a discussion of the pathophysiology of the disease. Issues of differential diagnosis and therapy are linked to pathophysiologic mechanisms. Short questions interspersed throughout the text require students to apply their knowledge. Detailed answers to the questions are included. New to this edition: Full-color artwork and design. New color photomicrographs of clinical conditions. Additional end-of-chapter summaries. Up-to-date information based on new medical findings