Basic concepts in medicinal chemistry / Marc W. Harrold, Robin M. Zavod.
By: Harrold, Marc W [author.].
Contributor(s): Zavod, Robin M [author.] | American Society of Health-System Pharmacists [issuing body.].
Publisher: Bethesda, MD : ASHP, ©2023Edition: 3rd edition.Description: 526 pages.Content type: text Media type: computer ISBN: 9781585286942.Subject(s): Chemistry, Pharmaceutical | Drug InteractionsGenre/Form: Examination Questions | Print books.Current location | Call number | Status | Date due | Barcode | Item holds |
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On Shelf | RS403 .H37 2023 (Browse shelf) | Available | AU00000000019694 |
Includes bibliographical references and index.
Functional Group Characteristics and Roles -- Identifying Acidic and Basic Functional Groups -- Solving pH and pKa Problems -- Salts and Solubility -- Drug Binding Interactions -- Stereochemistry and Drug Action -- Drug Metabolism -- Structure Activity Relationships and Basic Concepts in Drug Design -- Whole Molecule Drug Evaluation.
"This text will focus upon the basic, fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The text will include numerous examples of each concept as well as review questions designed to help readers assess their understanding of these concepts. Each chapter will also include a section that focuses upon the application of the pertinent concepts to therapeutic decisions. The text is meant to be comprehensive in regards to the fundamental chemical concepts that govern drug action; however, it will not discuss every drug or drug class. Through conceptual discussions, examples, and applications, the text should provider with the knowledge and skills to discuss the pertinent chemistry of drug molecules"--