Distribution and Phenotype of Proliferating Cells in the Forebrain of Adult Macaque Monkeys after Transient Global Cerebral Ischemia
Tonchev, Anton B.
Distribution and Phenotype of Proliferating Cells in the Forebrain of Adult Macaque Monkeys after Transient Global Cerebral Ischemia [electronic resource] / by Anton B. Tonchev, George N. Chaldakov, Tetsumori Yamashima. - X, 108 p. 65 illus. online resource. - Advances in Anatomy Embryology and Cell Biology, 191 0301-5556 ; . - Advances in Anatomy Embryology and Cell Biology, 191 .
1 Introduction.-.1 Studies on cell proliferation in adult primate brain -- 1.2 Methodological considerations in detecting cell proliferation -- 1.3 Cell proliferation in rodent brain after ischemia -- 1.4 Global cerebral ischemia in primates -- 2 Materials and Methods -- 2.1 Animal subjects -- 2.2 Bromodeoxyuridine infusion protocol -- 2.3 Tissue processing -- 2.4 Immunohistochemistry -- 2.5 Detection of DNA damage and degenerating cells -- 2.6 Electron microscopy -- 2.7 Image acquisition and analysis -- 2.8 Statistical analysis -- 3 Results -- 3.1 Hippocampal formation -- 3.1.1 Dentate gyrus -- 3.1.2 Cornu Ammonis -- 3.1.3 Subiculum -- 3.2 Subventricular zone of the inferior horn of the lateral ventricle (SVZi) -- 3.3 Temporal lobe -- 3.3.1 Parahippocampal region -- 3.3.2 Temporal neocortex -- 3.4 Subventricular zone of the anterior horn of the lateral ventricle (SVZa) -- 3.5 Rostral migratory stream and olfactory bulb -- 3.6 Frontal neocortex and striatum -- 4 Discussion -- 4.1 BrdU as a proliferation marker -- 4.2 Effects of ischemia on cell proliferation and differentiation -- 4.3 Sustained progenitor cell existence in germinative zones -- 4.4 Implications of monkey findings for therapies in humans -- 5 Summary -- References -- Subject Index.
(will follow).
9783540396178
10.1007/978-3-540-39617-8 doi
Medicine.
Neurosciences.
Biomedicine.
Neurosciences.
Electronic books.
RC321-580
612.8
Distribution and Phenotype of Proliferating Cells in the Forebrain of Adult Macaque Monkeys after Transient Global Cerebral Ischemia [electronic resource] / by Anton B. Tonchev, George N. Chaldakov, Tetsumori Yamashima. - X, 108 p. 65 illus. online resource. - Advances in Anatomy Embryology and Cell Biology, 191 0301-5556 ; . - Advances in Anatomy Embryology and Cell Biology, 191 .
1 Introduction.-.1 Studies on cell proliferation in adult primate brain -- 1.2 Methodological considerations in detecting cell proliferation -- 1.3 Cell proliferation in rodent brain after ischemia -- 1.4 Global cerebral ischemia in primates -- 2 Materials and Methods -- 2.1 Animal subjects -- 2.2 Bromodeoxyuridine infusion protocol -- 2.3 Tissue processing -- 2.4 Immunohistochemistry -- 2.5 Detection of DNA damage and degenerating cells -- 2.6 Electron microscopy -- 2.7 Image acquisition and analysis -- 2.8 Statistical analysis -- 3 Results -- 3.1 Hippocampal formation -- 3.1.1 Dentate gyrus -- 3.1.2 Cornu Ammonis -- 3.1.3 Subiculum -- 3.2 Subventricular zone of the inferior horn of the lateral ventricle (SVZi) -- 3.3 Temporal lobe -- 3.3.1 Parahippocampal region -- 3.3.2 Temporal neocortex -- 3.4 Subventricular zone of the anterior horn of the lateral ventricle (SVZa) -- 3.5 Rostral migratory stream and olfactory bulb -- 3.6 Frontal neocortex and striatum -- 4 Discussion -- 4.1 BrdU as a proliferation marker -- 4.2 Effects of ischemia on cell proliferation and differentiation -- 4.3 Sustained progenitor cell existence in germinative zones -- 4.4 Implications of monkey findings for therapies in humans -- 5 Summary -- References -- Subject Index.
(will follow).
9783540396178
10.1007/978-3-540-39617-8 doi
Medicine.
Neurosciences.
Biomedicine.
Neurosciences.
Electronic books.
RC321-580
612.8