Bone Metastasis (Record no. 244183)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04207nam a22004815i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-59259-892-2 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20160614135125.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 100301s2005 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781592598922 |
| -- | 978-1-59259-892-2 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1385/1592598927 |
| Source of number or code | doi |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Alfaisal Main Library |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC254-282 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MJCL |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED062000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.994 |
| Edition number | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Bone Metastasis |
| Medium | [electronic resource] : |
| Remainder of title | Experimental and Clinical Therapeutics / |
| Statement of responsibility, etc | edited by Gurmit Singh, Shafaat A. Rabbani. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE STATEMENTS | |
| Place of production, publication, distribution, manufacture | Totowa, NJ : |
| Name of producer, publisher, distributor, manufacturer | Humana Press, |
| Date of production, publication, distribution, manufacture | 2005. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XIII, 344 p. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content Type Term | text |
| Content Type Code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media Type Term | computer |
| Media Type Code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier Type Term | online resource |
| Carrier Type Code | cr |
| Source | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Cancer Drug Discovery and Development |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Fundamental Concepts -- Overview -- Parathyroid Hormone-Related Peptide and Malignancy -- Vitamin D and Vitamin D Analogs in Cancer Progression and Metastasis -- Role of TGF-? and IGF in Tumor Progression and Bone Metastases -- Biologic and Therapeutic Implications of Osteomimicry and Epithelial-Mesenchymal Transition in Prostate Cancer -- Roles of Immune-Cell-Derived Matrix Metalloproteinases in Tumor Growth and Metastasis -- Contribution of Osteopontin to the Development of Bone Metastasis -- Role of Interleukin-11 in Osteolytic Bone Metastasis -- Cell Adhesion Molecules in Tumor Metastasis -- PTHrP and Cancer -- Antithrombotics in Tumor Growth and Metastasis -- Therapeutic Strategies -- Challenges and Strategies in the Analysis of Multiple Events in Oncology -- Integrins -- Bone Metastasis and Pathological Fractures -- Role of Photodynamic Therapy for Bone Metastasis -- Docetaxel for Metastatic Cancer and Its Role in Combination Therapies for Advanced Prostate Cancer -- Use of Tetracyclines for Bone Metastases -- Role of Bisphosphonates in Skeletal Metastases -- Radiation Treatment of Bone Metastases. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Bone metastasis occurs in 60 to 85% of all breast, prostate, and lung cancer patients and is responsible for increasing morbidity. In Bone Metastasis: Experimental and Clinical Therapeutics, leading bone metastasis experts from around the world explain the molecular underpinnings of the process, review current treatment approaches, and outline future therapeutic strategies. On the basic science side, the authors illuminate the role of various autocrine, paracrine, and immunological factors involved in the progression and establishment of bone metastases, highlighting the physiological processes that lead to bone degradation, pain, angiogenesis, and dysregulation of bone turnover. On the therapeutic side, the authors discuss various strategies that appear to have promise and are currently deployed in treatment or at the experimental stage. They show how the treatment of bone metastases may need to be individualized through a combination of surgical, radiation, and/or pharmacological maneuvers. Their analysis of various pharmacogenomic parameters and tissue environmental factors sets the stage for progress beyond the current standards of using radiation and/or bisphosphonates for palliation. State-of-the-art and innovative, Bone Metastasis: Experimental and Clinical Therapeutics elucidates for all those involved-whether in research or clinical treatment of bone-seeking cancers-the biological processes and therapeutic advances that are already generating significant improvement in the cancer clinic. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Oncology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine & Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Oncology. |
| 655 #7 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| Source of term | local |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Singh, Gurmit. |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rabbani, Shafaat A. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9781588294036 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Cancer Drug Discovery and Development |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1385/1592598927">http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1385/1592598927</a> |
| 912 ## - | |
| -- | ZDB-2-SME |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Koha item type | eBooks |
No items available.