Conditional Mutagenesis: An Approach to Disease Models (Record no. 251119)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03979nam a22005655i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-540-35109-2 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20160614135727.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 100301s2007 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783540351092 |
| -- | 978-3-540-35109-2 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-540-35109-2 |
| Source of number or code | doi |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Alfaisal Main Library |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RM1-950 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MMG |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED071000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615 |
| Edition number | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Conditional Mutagenesis: An Approach to Disease Models |
| Medium | [electronic resource] / |
| Statement of responsibility, etc | edited by Robert Feil, Daniel Metzger. |
| 246 3# - VARYING FORM OF TITLE | |
| Title proper/short title | With contributions by numerous experts |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE STATEMENTS | |
| Place of production, publication, distribution, manufacture | Berlin, Heidelberg : |
| Name of producer, publisher, distributor, manufacturer | Springer Berlin Heidelberg, |
| Date of production, publication, distribution, manufacture | 2007. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XII, 532 p. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content Type Term | text |
| Content Type Code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media Type Term | computer |
| Media Type Code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier Type Term | online resource |
| Carrier Type Code | cr |
| Source | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Handbook of Experimental Pharmacology, |
| International Standard Serial Number | 0171-2004 ; |
| Volume number/sequential designation | 178 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Tools for Conditional Mutagenesis -- Conditional Somatic Mutagenesis in the Mouse Using Site-Specific Recombinases -- Cre/loxP-Mediated Chromosome Engineering of the Mouse Genome -- Tetracycline-Controlled Genetic Switches -- Novel Gene Switches -- Improved Embryonic Stem Cell Technologies -- Gene Trap Mutagenesis -- RNA Interference in Mice -- Viral Vectors: A Wide Range of Choices and High Levels of Service -- Conditional Mutagenesis by Cell-Permeable Proteins: Potential, Limitations and Prospects -- Examples of Conditional Disease Models -- Analysis of Mouse Development with Conditional Mutagenesis -- Conditional Mouse Models of Cancer -- Conditional Mutagenesis Reveals Immunological Functions of Widely Expressed Genes: Activation Thresholds, Homeostatic Mechanisms and Disease Models -- Conditional Transgenesis and Recombination to Study the Molecular Mechanisms of Brain Plasticity and Memory -- A Novel Conditional Knockout Strategy Applied to Serotonin Receptors -- Conditional Mouse Models for Friedreich Ataxia, a Neurodegenerative Disorder Associating Cardiomyopathy -- Animal Models in Cardiovascular Diseases: New Insights from Conditional Models -- Conditional Animal Models for the Study of Lipid Metabolism and Lipid Disorders -- Conditional Mouse Models to Study Developmental and Pathophysiological Gene Function in Muscle -- Analysis of Calcium Channels by Conditional Mutagenesis -- Conditional Mutagenesis of G-Protein Coupled Receptors and G-Proteins -- Contribution of Targeted Conditional Somatic Mutagenesis to Deciphering Retinoid X Receptor Functions and to Generating Mouse Models of Human Diseases. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse (part 1) and their application to model human physiology and pathophysiology (part 2). It illustrates how sophisticated genetic manipulations of the mouse genome are employed to model human diseases and to identify underlying molecular mechanisms. Finally the book considers the development of new drugs to treat them. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human genetics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Molecular biology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmacology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medical biochemistry. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmacology/Toxicology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Molecular Medicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human Genetics. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medical Biochemistry. |
| 655 #7 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| Source of term | local |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Feil, Robert. |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Metzger, Daniel. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9783540351085 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Handbook of Experimental Pharmacology, |
| -- | 0171-2004 ; |
| Volume number/sequential designation | 178 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-3-540-35109-2">http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-3-540-35109-2</a> |
| 912 ## - | |
| -- | ZDB-2-SBL |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Koha item type | eBooks |
No items available.