TGF-β Signaling (Record no. 257238)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04758nam a22005055i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-4939-2966-5 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20160615101053.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 151031s2016 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781493929665 |
| -- | 978-1-4939-2966-5 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-4939-2966-5 |
| Source of number or code | doi |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Alfaisal Main Library |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QH573-671 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSF |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | SCI049000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 571.6 |
| Edition number | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | TGF-β Signaling |
| Medium | [electronic resource] : |
| Remainder of title | Methods and Protocols / |
| Statement of responsibility, etc | edited by Xin-Hua Feng, Pinglong Xu, Xia Lin. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2016. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE STATEMENTS | |
| Place of production, publication, distribution, manufacture | New York, NY : |
| Name of producer, publisher, distributor, manufacturer | Springer New York : |
| -- | Imprint: Humana Press, |
| Date of production, publication, distribution, manufacture | 2016. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XII, 394 p. 64 illus., 41 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content Type Term | text |
| Content Type Code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media Type Term | computer |
| Media Type Code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier Type Term | online resource |
| Carrier Type Code | cr |
| Source | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Methods in Molecular Biology, |
| International Standard Serial Number | 1064-3745 ; |
| Volume number/sequential designation | 1344 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Regulation of TGF-b Receptors -- Determining TGF-β Receptor Levels in the Cell Membrane -- Post-translational Modifications of TGF-b Receptors -- Production, Isolation，and Structural Analysis of Ligands and Receptors of the TGF-b Superfamily -- Phosphorylation of Smads by Intracellular Kinases -- Analysis of Smad Phosphatase Activity in vitro -- Three-dimensional Mammary Epithelial Cell Morphogenesis Model for Analysis of TGF-b Signaling -- TGF-β Signaling in Stem Cell Regulation -- Analysis of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor β -- In vitro Th differentiation protocol -- Interrogating TGF-b Function and Regulation in Endothelial Cells -- Isolation and Manipulation of Adipogenic Cells to Assess TGF-b Superfamily Functions -- Imaging TGFb Signaling in Mouse Models of Cancer Metastasis -- Generation and Characterization of Smad7 Conditional Knockout Mice -- Monitoring Smad Activity in vivo Using the Xenopus Model System -- Animal Cap Assay for TGF-b Signaling -- Detection of Smad Signaling in Zebrafish Embryos -- Role of TGF-β signaling in Coupling Bone Remodeling -- Studying the Functions of TGF-β Signaling in the Ovary -- Quantitative Real-Time PCR Analysis of MicroRNAs and Their Precursors Regulated by TGF-b Signaling -- TGF-β Regulated microRNAs and Their Function in Cancer Biology -- Epigenomic Regulation Of Smad1 Signaling During Cellular Senescence Induced by Ras Activation -- The Role of Ubiquitination to Determine Non-Smad Signaling Responses -- Genome-wide RNAi Screening to Dissect the TGF-b Signal Transduction Pathway -- Measuring TGF-β Ligand Dynamics in Culture Medium. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-β from the basic principles to the practical applications. Chapters provide basic introduction of TGF-β signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-β signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Life sciences. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cell biology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Life Sciences. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cell Biology. |
| 655 #7 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| Source of term | local |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Feng, Xin-Hua. |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Xu, Pinglong. |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lin, Xia. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9781493929658 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Methods in Molecular Biology, |
| -- | 1064-3745 ; |
| Volume number/sequential designation | 1344 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-1-4939-2966-5">http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-1-4939-2966-5</a> |
| 912 ## - | |
| -- | ZDB-2-PRO |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Koha item type | eBooks |
No items available.