Towards a New Neuromorphology (Record no. 258720)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04706nam a22005175i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-319-25693-1 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20160615101122.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 151228s2016 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783319256931 |
| -- | 978-3-319-25693-1 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-319-25693-1 |
| Source of number or code | doi |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Alfaisal Main Library |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC321-580 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSAN |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED057000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 612.8 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nieuwenhuys, Rudolf. |
| Relator term | author. |
| 245 10 - TITLE STATEMENT | |
| Title | Towards a New Neuromorphology |
| Medium | [electronic resource] / |
| Statement of responsibility, etc | by Rudolf Nieuwenhuys, Luis Puelles. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2016. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE STATEMENTS | |
| Place of production, publication, distribution, manufacture | Cham : |
| Name of producer, publisher, distributor, manufacturer | Springer International Publishing : |
| -- | Imprint: Springer, |
| Date of production, publication, distribution, manufacture | 2016. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XV, 344 p. 133 illus., 95 illus. in color. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content Type Term | text |
| Content Type Code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media Type Term | computer |
| Media Type Code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier Type Term | online resource |
| Carrier Type Code | cr |
| Source | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1. From classic to modern neuromorphology, an introductory overview -- 2. The neural plate -- 3. From neural plate to neural tube -- 4. The neural tube -- 5. The axis of the brain, its flexures and correlates -- 6. The (complex) rostral part of the brain -- Summary -- 7. The natural coordinate system of the CNS -- 8. The fundamental morphological units (FMUs) of the CNS -- 9. The structural pattern, ’Bauplan’ or ‘blueprint’ of the CNS -- 10. The development of grisea -- 11. The ‘wiring’ of the brain -- 12. General summary, conclusions and perspective -- References -- Index. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | This book demonstrates that the systematic study of gene expression patterns in embryonic and adult brains, in combination with selected data from earlier studies, can pave the way for a new neuromorphology, the most salient features of which may be summarized as follows: (1) Causal analysis of molecular patterning at neural plate and early neural tube stages has shown that the CNS is essentially organized into transverse neural segments or neuromeres and longitudinal zones which follow the curved axis of the brain. (2) The FMUs initially represent thin neuroepithelial fields; in the course of further development they are transformed into three-dimensional radial units, extending from the ventricular surface to the meningeal surface of the brain. (3) The principal histogenetic processes, including cellular proliferation, cell migration and differentiation, essentially take place within the confines of these radial units, controlled by characteristic sets of developmental regulatory genes. (4) Although most developing neurons migrate radially and settle within their own FMU, at many locations neuroblasts leave the FMU where they were produced and migrate tangentially to other nearby or remote territories, colonizing parts of foreign FMUs. (5) Many structural complexes in the adult brain, including the cerebral and cerebellar cortices, are the products of radial and tangential intermingling of migrated cell contingents. (6) By using appropriate molecular markers, all neuron types in the adult CNS can be traced back to a specific progenitor zone within a specific FMU, and the progeny of any FMU can be traced to their final positions with the help of selective labeling approaches. (7) Early outgrowing axons form bundles, which tend to pass close to the border zones of the radial units. By means of their molecularly diversely tuned growth cones, these extending axons decide how to behave at each boundary they encounter, sometimes even reorienting at right angles. Collectively these early axonal bundles form a checkerboard-like scaffold, which accentuates the molecular regionalization of the CNS and leads to the formation of topographically ordered synaptic fields. The book covers all of these aspects in detail, providing a morphologic model (blueprint) that highlights the natural coordinates of CNS structure resulting from the conserved molecularly controlled shaping phenomena within morphogenetic fields. . |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurosciences. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurobiology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurosciences. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurobiology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurology. |
| 655 #7 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| Source of term | local |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Puelles, Luis. |
| Relator term | author. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9783319256924 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-3-319-25693-1">http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-3-319-25693-1</a> |
| 912 ## - | |
| -- | ZDB-2-SBL |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Koha item type | eBooks |
No items available.