Obesity Before Birth (Record no. 286887)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 05152nam a22005175i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-4419-7034-3 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20160615111347.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 130531s2011 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781441970343 |
| -- | 978-1-4419-7034-3 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-4419-7034-3 |
| Source of number or code | doi |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Alfaisal Main Library |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC648-665.2 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MJG |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED027000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.4 |
| Edition number | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Obesity Before Birth |
| Medium | [electronic resource] : |
| Remainder of title | Maternal and prenatal influences on the offspring / |
| Statement of responsibility, etc | edited by Robert H Lustig. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE STATEMENTS | |
| Place of production, publication, distribution, manufacture | Boston, MA : |
| Name of producer, publisher, distributor, manufacturer | Springer US : |
| -- | Imprint: Springer, |
| Date of production, publication, distribution, manufacture | 2011. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XIV, 414 p. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content Type Term | text |
| Content Type Code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media Type Term | computer |
| Media Type Code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier Type Term | online resource |
| Carrier Type Code | cr |
| Source | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Endocrine Updates, |
| International Standard Serial Number | 1566-0729 ; |
| Volume number/sequential designation | 30 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Preface -- Obesity: nature or nurture? -- The contribution of heredity to clinical obesity -- Monogenetic disorders within the energy balance pathway -- Ciliary syndromes and obesity -- Genome-wide association studies and human population obesity -- Known clinical epigenetic disorders with an obesity phenotype: Prader-Willi Syndrome and the GNAS locus -- Evidence for epigenetic changes as a cause of clinical obesity -- Epigenetic changes associated with intrauterine growth retardation and adipogenesis -- Exposure to diabetes in utero, offspring growth, and risk for obesity -- Maternal weight gain during pregnancy and obesity in the offspring -- Intrauterine growth restriction, small for gestational age, and experimental obesity -- Experimental models of maternal obesity and high-fat diet during pregnancy and programmed obesity in the offspring -- High carbohydrate intake only during the suckling period results in adult-onset obesity in mother as well as offspring -- Prenatal stress, glucocorticoids, and the metabolic syndrome -- Hypothalamic maldevelopment and developmental programming -- Adipocyte development and experimental obesity -- The obesogen hypothesis of obesity: overview and human evidence -- Perinatal exposure to endocrine disrupting chemicals with estrogenic activity and the development of obesity -- The role of environmental obesogens in the obesity epidemic. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Obesity obeys the First Law of Thermodynamics. The routine assumption is that obesity is the result of a mismatch between calories in and calories out; in other words, the result of two divergent behaviors. However, there is mounting evidence that biochemical forces can drive obligate weight gain, and that the observed behaviors of increased energy intake and decreased energy expenditure are secondary to these processes. Furthermore, many of these biochemical forces are determined in utero; resulting in a developmental drive toward obesity and disease in later life. Four distinct prenatal forces have thus far been identified: 1) genetics; 2) epigenetics; 3) developmental programming; and 4) environmental obesogens. This volume explores the evidence for each of these in detail in human and animal models, and attempts to provide a cohesive analysis of the biochemical bases of obesity. This volume will appeal to geneticists, developmental biologists, endocrinologists, epidemiologists, toxicologists, obstetrician/gynecologists, nutritionists, veterinary scientists, animal husbandry researchers, domestic species researchers, and obesity researchers and practitioners. "This very timely volume provides an in-depth scholarly overview of a critical challenge facing our society—the obesity epidemic. Dr. Robert H. Lustig has assembled expert authors to address the fundamental contribution of preprogrammed genetic disorders leading to obesity, as well as the role of very early environmental influences. The chapters range from classic genetic mechanistic understanding through intra-uterine epigenetic influences, factors determining developmental programming, and the new clinical science of perinatal obesogens. Obesity Before Birth: Maternal and prenatal influences on the offspring, brings easily accessible, cutting edge information to geneticists, pediatricians, endocrinologists, as well as those clinicians and scientists pursuing the complex yet elusive causes of childhood obesity and related disorders." - Shlomo Melmed, M.D. Series Editor. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human genetics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Food |
| General subdivision | Biotechnology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Endocrinology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine & Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Endocrinology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human Genetics. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Food Science. |
| 655 #7 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| Source of term | local |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lustig, Robert H. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9781441970336 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Endocrine Updates, |
| -- | 1566-0729 ; |
| Volume number/sequential designation | 30 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-1-4419-7034-3">http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-1-4419-7034-3</a> |
| 912 ## - | |
| -- | ZDB-2-SME |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Koha item type | eBooks |
No items available.