Immune Infertility (Record no. 297927)
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000 -LEADER | |
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fixed length control field | 04240nam a22005775i 4500 |
001 - CONTROL NUMBER | |
control field | 978-3-642-01379-9 |
003 - CONTROL NUMBER IDENTIFIER | |
control field | DE-He213 |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20160615112007.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
fixed length control field | cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 100301s2009 gw | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
International Standard Book Number | 9783642013799 |
-- | 978-3-642-01379-9 |
024 7# - OTHER STANDARD IDENTIFIER | |
Standard number or code | 10.1007/978-3-642-01379-9 |
Source of number or code | doi |
049 ## - LOCAL HOLDINGS (OCLC) | |
Holding library | Alfaisal Main Library |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
Classification number | RG133.5 |
072 #7 - SUBJECT CATEGORY CODE | |
Subject category code | MFKC |
Source | bicssc |
072 #7 - SUBJECT CATEGORY CODE | |
Subject category code | HEA039060 |
Source | bisacsh |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
Classification number | 612.6 |
Edition number | 23 |
245 10 - TITLE STATEMENT | |
Title | Immune Infertility |
Medium | [electronic resource] : |
Remainder of title | The Impact of Immune Reactions on Human Infertility / |
Statement of responsibility, etc | edited by Walter K.H. Krause, Rajesh K. Naz. |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE STATEMENTS | |
Place of production, publication, distribution, manufacture | Berlin, Heidelberg : |
Name of producer, publisher, distributor, manufacturer | Springer Berlin Heidelberg, |
Date of production, publication, distribution, manufacture | 2009. |
300 ## - PHYSICAL DESCRIPTION | |
Extent | XI, 236 p. |
Other physical details | online resource. |
336 ## - CONTENT TYPE | |
Content Type Term | text |
Content Type Code | txt |
Source | rdacontent |
337 ## - MEDIA TYPE | |
Media Type Term | computer |
Media Type Code | c |
Source | rdamedia |
338 ## - CARRIER TYPE | |
Carrier Type Term | online resource |
Carrier Type Code | cr |
Source | rdacarrier |
347 ## - | |
-- | text file |
-- | |
-- | rda |
505 0# - FORMATTED CONTENTS NOTE | |
Formatted contents note | Sperm Antigens -- Proteomics of Human Spermatozoa -- Methods of Analysis of Sperm Antigens Related to Fertility -- Sperm Surface Proteomics -- Sperm Functions Influenced by Immune Reactions -- Antisperm Antibodies (ASA) -- The Immune Privilege of the Testis -- Immune Chemistry of ASA -- Sperm-Specific T Lymphocytes -- Site and Risk Factors of Antisperm Antibodies Production in the Male Population -- Biologic Substrates Containing ASA -- ASA in the Female -- Sperm-Immobilizing Antibody and Its Target Antigen (CD52) -- The Clinical Impact of Sperm Antibodies -- Male Autoimmune Infertility -- Tests for Sperm Antibodies -- Impact on Fertility Outcome -- Sperm Antibodies and Assisted Reproduction -- Treatment of Immune Infertility -- Immune Contraception -- Immunization with Sperm Antigens to Induce Contraception -- Immunocontraception in Wildlife Animals -- Experience from Clinical Trials with Fertility Control Vaccines. |
520 ## - SUMMARY, ETC. | |
Summary, etc | Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the female partner. Immune reactions to sperm can contribute up to 2–30% of infertility. The sperm has both autoantigenic as well as isoantigenic potential, and is thus capable of p- ducing antisperm antibodies (ASAs) and sperm-reactive T cells in both infertile men and women. Also, over 75% vasectomized men produce autoantibodies to sperm that can cause a problem in regaining fertility even after successful re-anastomosis in vasovasostomy. Early claims regarding the incidence and involvement of ASAs in involuntary human infertility were probably overemphasized because of unreliable techniques and naivety concerning the complexity of the immune response and antigenic nature of the sperm cell. These factors, the lack of well-designed and controlled experimental studies, and the dearth of effective therapeutic modalities resulted in the confusion of the occurrence and importance of ASAs in human infertility. Consequently, evaluation of infertile couples for ASAs and their possible role in infertility was not considered a signifcant proposition. The development of more accurate assays and the discovery of mucosal immunity capable of responses independent of systemic immunity have caused inclusion of sperm cells and genital tract secretions in the analysis of ASAs. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Medicine. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Immunology. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Dermatology. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | General practice (Medicine). |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Gynecology. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Reproductive medicine. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Urology. |
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Medicine & Public Health. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Reproductive Medicine. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Gynecology. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Urology. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Immunology. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | General Practice / Family Medicine. |
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name as entry element | Dermatology. |
655 #7 - INDEX TERM--GENRE/FORM | |
Genre/form data or focus term | Electronic books. |
Source of term | local |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Krause, Walter K.H. |
Relator term | editor. |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Naz, Rajesh K. |
Relator term | editor. |
710 2# - ADDED ENTRY--CORPORATE NAME | |
Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY | |
Title | Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
Display text | Printed edition: |
International Standard Book Number | 9783642013782 |
856 40 - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-3-642-01379-9">http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-3-642-01379-9</a> |
912 ## - | |
-- | ZDB-2-SME |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | Library of Congress Classification |
Koha item type | eBooks |
No items available.