Thresholds of genotoxic carcinogens : (Record no. 540876)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04810cam a2200553Ii 4500 |
| 001 - CONTROL NUMBER | |
| control field | ocn950518680 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20180529115737.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160525s2016 enk o 001 0 eng d |
| 019 ## - | |
| -- | 951222629 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780128018033 |
| Qualifying information | electronic bk. |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0128018038 |
| Qualifying information | electronic bk. |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 9780128016633 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 0128016639 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)950518680 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | DLC |
| Language of cataloging | eng |
| Transcribing agency | DLC |
| Modifying agency | AU |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | Alfaisal Main Library |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RA1224.3 |
| 245 00 - TITLE STATEMENT | |
| Title | Thresholds of genotoxic carcinogens : |
| Remainder of title | from mechanisms to regulation / |
| Statement of responsibility, etc | edited by Takehiko Nohmi, Shoji Fukushima. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE STATEMENTS | |
| Place of production, publication, distribution, manufacture | London, UK : |
| Name of producer, publisher, distributor, manufacturer | Academic Press is an imprint of Elsevier, |
| Date of production, publication, distribution, manufacture | 2016. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Date of publication, distribution, etc | 2016. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource. |
| 336 ## - CONTENT TYPE | |
| Content Type Term | text |
| Content Type Code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media Type Term | computer |
| Media Type Code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier Type Term | online resource |
| Carrier Type Code | cr |
| Source | rdacarrier |
| 500 ## - GENERAL NOTE | |
| General note | Includes index. |
| 588 0# - | |
| -- | Online resource; title from PDF title page (ScienceDirect, viewed June 6, 2016). |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Title page; Table of Contents; Copyright; List of Contributors; Preface; Chapter 1. Qualitative and Quantitative Assessments on Low-Dose Carcinogenicity of Genotoxic Hepatocarcinogens: Dose-Response for Key Events in Rat Hepatocarcinogenesis; Abstract; Introduction; Qualitative and Quantitative Analyses on Low-Dose Carcinogenicity of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline in the Rat Liver; Qualitative and Quantitative Analyses on Low-Dose Hepatocarcinogenicity of 2-Amino-3-methylimidazo[4,5-f]quinoline in the Rat Liver |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Qualitative and Quantitative Analysis on Low-Dose Hepatocarcinogenicity of N-nitrosodiethylamine in the Rat LiverDiscussion; References; Chapter 2. Thresholds for Hepatocarcinogenicity of DNA-Reactive Compounds; Abstract; Introduction; Dose-Effect Studies of Initiation of Liver Carcinogenesis; Conclusions; Relevance to Humans; References; Chapter 3. Interaction of Low-Dose Radiation and Chemicals in Cancer Risk; Abstract; Epidemiological Analysis of Cancer Risk; Interaction of Radiation and Other Carcinogens; Data From Animal Experiments; Conclusion; Acknowledgments; References |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Chapter 4. Possible Mechanisms Underlying Genotoxic Thresholds: DNA Repair and Translesion DNA SynthesisAbstract; Introduction; Challenges in Identification of Genotoxicity of Chemicals; Possible Mechanisms Underlying Genotoxic Thresholds; Significance of DNA Repair Mechanisms in the Suppression of Mutagenesis and Tumorigenesis in Mammals; TLS as a Critical Factor for Mutagenesis; Future Perspectives; Acknowledgments; References; Chapter 5. DNA Repair and Its Influence on Points of Departure for Alkylating Agent Genotoxicity; Abstract; Introduction |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | The Paradigm Shift in Response to Low Doses of Alkylating AgentsAlkylating Agent Mechanism of Action; DNA Repair of Alkyl Adducts: Potential Influences on PoDs; Mechanistic Evidence Supporting a PoD for EMS; Mechanistic Evidence Supporting a PoD for ENU; Mechanistic Evidence Supporting a PoD for MMS; Mechanistic Evidence Supporting a PoD for MNU; Concluding Remarks; References; Chapter 6. The Role of Endogenous Versus Exogenous DNA Damage in Risk Assessment; Abstract; Introduction; Aldehydes; Alkylating Agents; Oxidative Stress; Ionizing Radiation |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Quantifying Complex Dose-Response Relationships to Support Risk AssessmentsConclusion; References; Chapter 7. Thresholds of Toxicological Concern for Genotoxic Impurities in Pharmaceuticals; Abstract; Introduction; Genotoxic and Nongenotoxic Carcinogens; Thresholds of Chemical Genotoxicity; Risk Management for Genotoxic Carcinogens; Risk Assessment and Control of Genotoxic Impurities in Pharmaceuticals; Conclusion; References; Chapter 8. Practical Thresholds in the Derivation of Occupational Exposure Limits (OELs) for Carcinogens; Abstract; Introduction |
| 590 ## - LOCAL NOTE (RLIN) | |
| Local note | Elsevier |
| Provenance (VM) [OBSOLETE] | ScienceDirect All Books |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Genetic toxicology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Carcinogenesis. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | HEALTH & FITNESS / Diseases / General |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL / Clinical Medicine |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL / Diseases |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL / Evidence-Based Medicine |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL / Internal Medicine |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Carcinogenesis. |
| Source of heading or term | fast |
| -- | (OCoLC)fst00846974 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Genetic toxicology. |
| Source of heading or term | fast |
| -- | (OCoLC)fst00940097 |
| 655 #7 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| Source of term | local |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nohmi, Takehiko, |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fukushima, Shoji, |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | ScienceDirect eBooks. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Print version: |
| Main entry heading | Nohmi, Takehiko |
| Title | Thresholds of Genotoxic Carcinogens : From Mechanisms to Regulation |
| Place, publisher, and date of publication | : Elsevier Science,c2016 |
| International Standard Book Number | 9780128016633 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://ezproxy.alfaisal.edu/login?url=https://www.sciencedirect.com/science/book/9780128016633">http://ezproxy.alfaisal.edu/login?url=https://www.sciencedirect.com/science/book/9780128016633</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Koha item type | eBooks |
No items available.