Bone Marrow and Stem Cell Transplantation [electronic resource] / edited by Meral Beksac.
Series: Methods in Molecular Medicine ; 134Publisher: Totowa, NJ : Humana Press, 2007Description: X, 234 p. online resourceContent type:- text
- computer
- online resource
- 9781597452236
- 616.15 23
- RB45

Molecular Profiling of Hematopoietic Stem Cells -- Methods for Imaging Cell Fates in Hematopoiesis -- An Overview of HLA Typing for Hematopoietic Stem Cell Transplantation -- Sequence-Specific Primed PCR (PCR-SSP) Typing of HLA Class I and Class II Alleles -- HLA Typing with Sequence-Specific Oligonucleotide Primed PCR (PCR-SSO) and Use of the Luminex™ Technology -- Sequencing-Based Typing of HLA -- Molecular Typing Methods for Minor Histocompatibility Antigens -- Non-HLA Gene Polymorphisms in Stem Cell Transplantation -- Polymorphisms Within Epithelial Receptors -- Role of Natural Killer Cells and Killer Immunoglobulin-Like Receptor Polymorphisms -- Identification of Bone Marrow Derived Nonhematopoietic Cells by Double Labeling with Immunohistochemistry and In Situ Hybridization -- Molecular Methods Used for Detection of Minimal Residual Disease Following Hematopoietic Stem Cell Transplantation in Myeloid Disorders -- Molecular Methods Used for The Detection of Autologous Graft Contamination in Lymphoid Disorders -- Detection of Impending Graft Rejection and Relapse by Lineage-Specific Chimerism Analysis -- Application of Proteomics to Posttransplantational Follow-Up.
Molecular Methods: Stem Cell Transplantation presents a compendium of cutting-edge research on the molecular steps involved in hematopoietic stem cell (HSC) activation and self-renewal. The emergence of HLA typing, and the positive impact it has had on the success of clinical transplantation is emphasized and discussed by notable stem cell researchers.