Includes bibliographical references and index.

Uremic toxins : an integrated overview of definition and classification / Richard J. Glassock and Shaul G. Massry -- Classification and a list of uremic toxins / Nathalie Neirynck ... [et al.] -- Analysis of uremic toxins with mass spectrometry? / Toshimitsu Niwa -- Indoxyl sulfate / Toshimitsu Niwa -- P-cresyl sulfate / Anneleen Pletinck, Raymond Vanholder, and Griet Glorieux -- 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid / Toshimitsu Niwa -- Phenylacetic acid / Anna Schulz and Joachim Jankowski -- Homocysteine and hydrogen sulfide : two opposing aspects in the pathobiology of sulfur compounds in chronic renal failure / Alessandra F. Perna and Diego Ingrosso -- Guanidino compounds / Sunny Eloot ... [et al.] -- Asymmetric dimethylarginine / Vladimir Teplan and Jaroslav Racek -- Nicotinamide metabolites / Przemyslaw Rutkowski and Boleslaw Rutkowski -- Dicarbonyls (glyoxal, methylglyoxal, and 3-deoxyglucosone) / Naila Rabbani and Paul J. Thornalley -- Glucose degradation products in peritoneal dialysis / Monika Pischetsrieder and Sabrina Gensberger -- Dinucleoside polyphosphates / Joachim Jankowski and Vera Jankowski -- Parathyroid hormone / Shaul G. Massry and Miroslaw Smogorzewski -- 2-microglobulin / Suguru Yamamoto ... [et al.] -- Cytokines / Bjorn Anderstam, Bengt Lindholm, and Peter Stenvinkel -- Free immunoglobulin light chains / Gerald Cohen and Walter H. Hirl -- Advanced glycation end-products (AGEs) / Naila Rabbani and Paul J. Thornalley -- Oxidized albumin / Maurizio Bruschi ... [et al.] -- Therapeutic removal of uremic toxins by hemodialysis / Tammy L. Sirich, Pavel Aronov, and Timothy W. Meyer -- Therapeutic removal of uremic toxins by peritoneal dialysis / Malgorzata Debowska ... [et al.] -- Therapeutic removal of uremic toxins by oral sorbent / Toshimitsu Niwa.

The book is split into four parts 1) definition, classification and a list of uremic toxins, 2) application of MS for uremic toxin research, 3) description of selected uremic toxins such as chemical structure, metabolism, analytical methods, serum levels, toxicity and clinical implication, and removal methods, and 4) therapeutic removal of uremic toxins by hemodialysis, peritoneal dialysis and oral sorbent.

John Wiley and Sons Wiley eBooks