High-throughput screening methods in toxicity testing / edited by Pablo Steinberg.

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Publication details: Hoboken, New Jersey : John Wiley & Sons Inc., [2013]Description: 1 online resourceContent type:

text

Media type:

computer

Carrier type:

online resource

ISBN:

9781118538180
1118538188
9781118538203
111853820X
9781299252592
1299252591

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Genre/Form:

Electronic books.

Additional physical formats: Print version:: High-throughput screening methods in toxicity testing.LOC classification:

RS419.5 .H542 2013eb

Online resources:

Contents:

pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity.

Summary: "High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"-- Provided by publisher.Summary: "This book describes the high-throughput in vitro methods available for toxicity testing, serving as a guide to scientists working in toxicity evaluation and risk assessment of chemicals and drugs"-- Provided by publisher.

Item type:

eBooks

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Includes index.

"High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"-- Provided by publisher.

"This book describes the high-throughput in vitro methods available for toxicity testing, serving as a guide to scientists working in toxicity evaluation and risk assessment of chemicals and drugs"-- Provided by publisher.

Includes bibliographical references and index.

John Wiley and Sons Wiley eBooks