Includes bibliographical references (pages 346-349) and index.

Machine generated contents note: Part I: Fundamental ConceptsIntroduction: Colwell1. Molecular clockwork and the determinants of human circadian clock Steve Brown, University of Zurich,2.SCN Circuitry with a focus on outputs including ANS, body temperature Rae Silver, Columbia University, Ruud Buijs, Universidad Nacional Autonoma de Mexico3. Sleep and circadian rhythms: partners in the regulation of behavior. Mistlberger RE, Simon Fraser University, Burnaby, BC, Canada OR T. Deboer, Leiden University, NL4. Circadian Sleep disorders Phyllis C. Zee, Sleep Disorders Center, Northwestern University OR Derk-Jan Dijk, University of Surrey5. Sleep and circadian rhythms: reciprocal partners in the regulation of behavior. Mistlberger RE, Simon Fraser University, Burnaby, BC, Canada or T. Deboer, Leiden Univeristy, NL6. Circadian regulation of arousal and role in chronic fatigue / Mary Harrington, Smith College Part II: Circadian regulation of major organ system7. Physiology of the adrenal and liver circadian clocks / Henrik Oster, Max-Planck Institute Biophysical Chemistry Goettingen Germany8. Nutrition and diet as potent regulators of the liver clock. Shigenobu Shibata; Waseda University, Tokyo, Japan;9. Desynchrony of the human circadian system as a cause of pathophysiology in the heart and pancreas.Frank Scheer, Harvard University,10. Cardiomyocyte circadian clock OR Circadian Clocks in the Vasculature M.E. Young, University of Alabama; Garret A. Fitzgerald, M.D (University of Pennsylvania)11. Integration of Circadian Mechanisms and Energy Balance Joseph Bass, Northwestern University12. Disruption of circadian rhythms and development of diabetes Aleksey V. Matveyenko, University of California Los Angeles13. Respiratory clocks Hitoshi Okamura, Kyoto University, Japan14. Circadian clock control of the cellular response to DNA damage and cancer. Sancar, A, University of North Carolina School of Medicine, Chapel Hill, NCPart III: clocks in the central nervous system:15. Sleep and circadian regulation of vigilance and cognitive performance in humans Ken P Wright, Jr. Center for Neuroscience, University of Colorado, Boulder, CO16. Circadian clock, reward, and addictive behaviors Albrecht U, University of Fribourg, Fribourg, Switzerland:17. Circadian rhythms and mood disorders McClung, CA; University of Pittsburgh Medical School, 18. Circadian regulation of memory processes Colwell CSPart IV: Aging and neurodegeneration19. Is circadian dysfunction an integral symptom of Schizophrenia? Foster RG, University of Oxford, Oxford, UK20. Alzheimer's disease and the mistiming of behavior. Antle M, University of Calgary, Calgary, Canada21. Circadian dysfunctional in Huntington's disease Morton AJ, University of Cambridge, Cambridge, United Kingdom22. The Aging clock Block GD, University of California Los Angeles:23. Social jet lag and the costs of 24/7 society Till Roenneberg, Ludwig-Maximilians-University Munich24. How shift work and a destabilized circadian system may increase risk for development of cancer and type 2 diabetes. Eva Schemhammer, Harvard University.

"Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease.Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration.Written in an accessible and informative style, Circadian Rhythms: Health and Disease,will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology"--Provided by publisher.