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Applied biopharmaceutics & pharmacokinetics Leon Shargel, Andrew B.C. Yu, Susanna Wu-Pong.

By: Shargel, Leon, 1941-.
Contributor(s): Yu, Andrew B. C, 1945- | Wu-Pong, Susanna.
Publisher: New York : McGraw-Hill, 2012Edition: 6th ed.ISBN: 9780071603935.Other title: Applied biopharmaceutics and pharmacokinetics.Subject(s): Biopharmaceutics | Pharmacokinetics | Biopharmaceutics | Models, Chemical | PharmacokineticsGenre/Form: Print books.
Contents:
Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease.
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Current location Call number Status Date due Barcode Item holds
On Shelf RM301.4 .S52 2012 (Browse shelf) Available AU0000000007405
Total holds: 0

Includes bibliographical references and index.

Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease.

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Provider: McGraw Hill Companies.

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