AID for Immunoglobulin Diversity / edited by Frederick W. Alt and Tasuku Honjo.

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Series: Advances in immunology ; v. 94.Publisher: Amsterdam ; Boston, Mass. : Academic Press, 2007Description: 1 online resource (xv, 321 pages) : illustrations (some color)Content type:

text

Media type:

computer

Carrier type:

online resource

ISBN:

9780080545929
0080545920
0123737060
9780123737069
1281037222
9781281037220

Subject(s):

Genre/Form:

Electronic books.

Additional physical formats: Print version:: Aid for immunoglobulin diversity.LOC classification:

QR186.7 .A33 v.94eb

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Click here to access online

Contents:

Discovery of Activation-Induced Cytidine Deaminase, the Engraver of Antibody Memory -- DNA Deamination in Immunity: AID in the Context of Its APOBEC Relatives -- The Role of Activation-Induced Deaminase in Antibody Diversification and Chromosome Translocations -- Targeting of AID-Mediated Sequence Diversification by cis-Acting Determinants -- AID-Initiated Purposeful Mutations in Immunoglobulin Genes -- Evolution of the Immunoglobulin Heavy Chain Class Switch Recombination Mechanism -- Beyond SHM and CSR: AID and Related Cytidine Deaminases in the Host Response to Viral Infection -- Role of AID in Tumorigenesis -- Pathophysiology of B-Cell Intrinsic Immunoglobulin Class Switch Recombination Deficiencies.

Summary: Advances in Immunology, a long established and highly respected serial, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

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eBooks

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Text in English.

Includes bibliographical references and index.

Advances in Immunology, a long established and highly respected serial, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Print version record.

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