Volume Transmission Revisited / edited by L.F. Agnati, K. Fuxe, C. Nicholson, E. Sykova.

Contributor(s):

Series: Progress in brain research ; v. 125.Publisher: Amsterdam ; New York : Elsevier, 2000Description: 1 online resource (xv, 450 pages) : illustrationsContent type:

text

Media type:

computer

Carrier type:

online resource

ISBN:

0444503145
9780444503145

Subject(s): Genre/Form:

Electronic books.

Additional physical formats: Print version:: Volume transmission revisited.LOC classification:

QP376 .P7 v.125eb

NLM classification:

W1
WL 102.8

Online resources:

Click here to access online

Contents:

Conceptual basis of VT -- Diffusion and extracellular space -- Glia-neuronal signaling -- Monoamines and VT -- Wider world of VT-from ions to peptides.

Action note:

digitized 2010 HathiTrust Digital Library committed to preserve

Summary: Volume Transmission Revisited describes the mounting evidence that cells of the central nervous system are able to communicate via a host of chemical signals that flow through the extracellular space. Volume transmission (VT) constitutes a novel and complementary communication system to classical synaptic transmission. The new modality, which does not require specific connections between cells, leads to a reconsideration of the spatial relationships of neurons and glia, brings a new dimension to network modelling and is relevant to both short term interactions and long term tonic states of the brain. The reader will find 29 chapters describing many of the major discoveries in VT during the last decade. The most striking feature of this publication is the collecting together of many compelling examples of the ubiquitous nature of VT. These point to its increasing relevance from basic neuroscience research to clinical practice. Those working in other areas will find numerous invaluable examples of how leading investigators have gone about assembling evidence for VT.

Item type:

eBooks

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Text in English.

Includes bibliographical references and index.

Conceptual basis of VT -- Diffusion and extracellular space -- Glia-neuronal signaling -- Monoamines and VT -- Wider world of VT-from ions to peptides.

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Electronic reproduction. [S.l.] : HathiTrust Digital Library, 2010. MiAaHDL

Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL

http://purl.oclc.org/DLF/benchrepro0212

digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL

Volume Transmission Revisited describes the mounting evidence that cells of the central nervous system are able to communicate via a host of chemical signals that flow through the extracellular space. Volume transmission (VT) constitutes a novel and complementary communication system to classical synaptic transmission. The new modality, which does not require specific connections between cells, leads to a reconsideration of the spatial relationships of neurons and glia, brings a new dimension to network modelling and is relevant to both short term interactions and long term tonic states of the brain. The reader will find 29 chapters describing many of the major discoveries in VT during the last decade. The most striking feature of this publication is the collecting together of many compelling examples of the ubiquitous nature of VT. These point to its increasing relevance from basic neuroscience research to clinical practice. Those working in other areas will find numerous invaluable examples of how leading investigators have gone about assembling evidence for VT.

Print version record.

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