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Atlas of zebrafish development / Robert Bryson-Richardson, Silke Berger, Peter Currie.

By: Contributor(s): ©2012Edition: 1st edDescription: 1 online resource (232 pages) : illustrationsContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9780123740168
  • 0123740169
  • 9780080920610
  • 0080920616
Subject(s): Genre/Form: LOC classification:
  • QL638.C94 B79 2012
Online resources:
Contents:
I. Introduction. Chapter 1. Introduction -- Chapter 2. FishNet: An Interactive Database of Zebrafish Development -- Chapter 3. Methodology and Interpretation of the Atlas -- II. The Early Embryo. Chapter 4. 24hours -- Chapter 5. 48 hours -- Chapter 6. 72 hours -- Chapter 7. 96 hours -- Chapter 8. 120 hours -- III. The Developing Larvae. Chapter 9. 5-7mm -- Chapter 10. 8-10mm -- Chapter 11. 10-14mm -- IV. The Adult Zebrafish -- Chapter 12. 15-17mm.
Summary: Zebrafish are widely considered the best model for vertebrate development. The embryo is transparent, thereby enabling visualization and use of labelling and transgenic approaches. Moreover, because of the ease of inducing new mutations in zebrafish and similarity with the human genome, this organism may be used effectively for disease studies. For example, mutant zebrafish are being utilized for testing drugs that will combat a range of human diseases, from Alzheimer's and cancer to kidney failure and congenital heart disease. For the first time, this atlas provides the research community with a complete reference for zebrafish anatomy spanning the early embryo all the way to adulthood. The authors employ the technique of optical projection tomography (OPT), and offer a series of sections in multiple planes from each sample. The contents are organized by developmental stages, with over 200 images that contain annotations describing anatomical structures relevant to development. In addition, chapters feature explanatory text that highlights major developments in the zebrafish during each stage.
Item type: eBooks
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Includes bibliographical references (page 227) and index.

Zebrafish are widely considered the best model for vertebrate development. The embryo is transparent, thereby enabling visualization and use of labelling and transgenic approaches. Moreover, because of the ease of inducing new mutations in zebrafish and similarity with the human genome, this organism may be used effectively for disease studies. For example, mutant zebrafish are being utilized for testing drugs that will combat a range of human diseases, from Alzheimer's and cancer to kidney failure and congenital heart disease. For the first time, this atlas provides the research community with a complete reference for zebrafish anatomy spanning the early embryo all the way to adulthood. The authors employ the technique of optical projection tomography (OPT), and offer a series of sections in multiple planes from each sample. The contents are organized by developmental stages, with over 200 images that contain annotations describing anatomical structures relevant to development. In addition, chapters feature explanatory text that highlights major developments in the zebrafish during each stage.

I. Introduction. Chapter 1. Introduction -- Chapter 2. FishNet: An Interactive Database of Zebrafish Development -- Chapter 3. Methodology and Interpretation of the Atlas -- II. The Early Embryo. Chapter 4. 24hours -- Chapter 5. 48 hours -- Chapter 6. 72 hours -- Chapter 7. 96 hours -- Chapter 8. 120 hours -- III. The Developing Larvae. Chapter 9. 5-7mm -- Chapter 10. 8-10mm -- Chapter 11. 10-14mm -- IV. The Adult Zebrafish -- Chapter 12. 15-17mm.

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