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Ultrasmall lanthanide oxide nanoparticles for biomedical imaging and therapy / Gang Ho Lee, Yongmin Chang and Tae-Jeong Kim.

By: Contributor(s): Series: Woodhead Publishing series in biomaterials ; no. 68.Publisher: Cambridge : Woodhead Publishing, 2014Copyright date: ©2014Description: 1 online resourceContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9780081000694
  • 0081000693
Subject(s): Genre/Form: Additional physical formats: Print version:: Ultrasmall lanthanide oxide nanoparticles for biomedical imaging and therapy.LOC classification:
  • R857.O6 L44 2014
Online resources:
Contents:
Cover; Ultrasmall lanthanide oxide nanoparticles for biomedical imaging and therapy; Copyright; Dedication; Contents; List of figures and tables; List of abbrevations; Acknowledgments; Preface; About the authors; 1 Introduction to biomedical imaging; 1.1 What is biomedical imaging?; 1.2 Various imaging modalities now available; 1.3 References; 2 Properties and possible application areas; 2.1 Introduction; 2.2 Possible application areas; 2.3 References; 3 Synthesis and surface modification; 3.1 Synthesis; 3.2 Surface coating; 3.3 Other lanthanide nanosystems; 3.4 References; 4 Characterization.
4.1 Introduction4.2 Particle diameter and morphology; 4.3 Crystal structure; 4.4 Hydrodynamic diameter; 4.5 Surface coating confirmation; 4.6 Surface coating amount; 4.7 Magnetic properties; 4.8 Cytotoxicity; 4.9 Water proton relaxivity and map image; 4.10 Biodistribution; 4.11 In vivo TEM analysis of nanoparticles; 4.12 Fluorescent properties; 4.13 References; 5 MRI, CT, FI, and multimodal imaging and images; 5.1 Magnetic resonance imaging (MRI) and images; 5.2 X-ray computed tomography (CT) and images; 5.3 Fluorescent imaging (FI) and images; 5.4 Multimodal imaging; 5.5 References.
6 A simple model calculation of water proton relaxivities6.1 Introduction; 6.2 Magnetization; 6.3 Longitudinal water proton relaxation (T1) and relaxivity (r1); 6.4 Transverse water proton relaxation (T2) andrelaxivity (r2); 6.5 Concluding remarks; 6.6 References; 7 Thermal neutron capture therapy (NCT); 7.1 Introduction; 7.2 BNCT; 7.3 GdNCT; 7.4 References; 8 Perspectives and challenges; 8.1 Perspectives and challenges; 8.2 What needs to be done for clinical applications; Index.
Summary: Most books discuss general and broad topics regarding molecular imagings. However, Ultrasmall Lanthanide Oxide Nanoparticles for Biomedical Imaging and Therapy, will mainly focus on lanthanide oxide nanoparticles for molecular imaging and therapeutics. Multi-modal imaging capabilities will discussed, along with up-converting FI by using lanthanide oxide nanoparticles. The synthesis will cover polyol synthesis of lanthanide oxide nanoparticles, Surface coatings with biocompatible and hydrophilic ligands will be discussed and TEM images and dynamic light scattering (DLS) patterns will be provid.
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Cover; Ultrasmall lanthanide oxide nanoparticles for biomedical imaging and therapy; Copyright; Dedication; Contents; List of figures and tables; List of abbrevations; Acknowledgments; Preface; About the authors; 1 Introduction to biomedical imaging; 1.1 What is biomedical imaging?; 1.2 Various imaging modalities now available; 1.3 References; 2 Properties and possible application areas; 2.1 Introduction; 2.2 Possible application areas; 2.3 References; 3 Synthesis and surface modification; 3.1 Synthesis; 3.2 Surface coating; 3.3 Other lanthanide nanosystems; 3.4 References; 4 Characterization.

4.1 Introduction4.2 Particle diameter and morphology; 4.3 Crystal structure; 4.4 Hydrodynamic diameter; 4.5 Surface coating confirmation; 4.6 Surface coating amount; 4.7 Magnetic properties; 4.8 Cytotoxicity; 4.9 Water proton relaxivity and map image; 4.10 Biodistribution; 4.11 In vivo TEM analysis of nanoparticles; 4.12 Fluorescent properties; 4.13 References; 5 MRI, CT, FI, and multimodal imaging and images; 5.1 Magnetic resonance imaging (MRI) and images; 5.2 X-ray computed tomography (CT) and images; 5.3 Fluorescent imaging (FI) and images; 5.4 Multimodal imaging; 5.5 References.

6 A simple model calculation of water proton relaxivities6.1 Introduction; 6.2 Magnetization; 6.3 Longitudinal water proton relaxation (T1) and relaxivity (r1); 6.4 Transverse water proton relaxation (T2) andrelaxivity (r2); 6.5 Concluding remarks; 6.6 References; 7 Thermal neutron capture therapy (NCT); 7.1 Introduction; 7.2 BNCT; 7.3 GdNCT; 7.4 References; 8 Perspectives and challenges; 8.1 Perspectives and challenges; 8.2 What needs to be done for clinical applications; Index.

Most books discuss general and broad topics regarding molecular imagings. However, Ultrasmall Lanthanide Oxide Nanoparticles for Biomedical Imaging and Therapy, will mainly focus on lanthanide oxide nanoparticles for molecular imaging and therapeutics. Multi-modal imaging capabilities will discussed, along with up-converting FI by using lanthanide oxide nanoparticles. The synthesis will cover polyol synthesis of lanthanide oxide nanoparticles, Surface coatings with biocompatible and hydrophilic ligands will be discussed and TEM images and dynamic light scattering (DLS) patterns will be provid.

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