Includes bibliographical references and index.

Print version record.

Front Cover; Antiphospholipid Syndrome in Systemic Autoimmune Diseases; Copyright Page; Contents; List of Contributors; Foreword; Dedication; 1 History, Classification, and Subsets of the Antiphospholipid Syndrome; 1.1 Introduction; 1.2 Historical Perspective; 1.3 Classification of APS; 1.4 Primary or Isolated APS; 1.5 APS Associated With Other Diseases; 1.5.1 APS Associated With Autoimmune Diseases; 1.5.2 APS Associated With Infections; 1.5.3 APS Associated With Drugs; 1.5.4 APS Associated With Malignancies; 1.6 Seronegative APS; 1.7 Catastrophic APS; 1.8 International aPL/APS Congresses.

880-01 4.2.4 Antiprothrombin Antibodies4.2.5 Antibodies to Negatively Charged Phospholipids Other Than Cardiolipin; 4.2.6 Antibodies to Phosphatidylethanolamine; 4.2.7 Other aPL Specificities; 4.3 Lupus Anticoagulant; 4.4 Annexin A5 Resistance Test: A Mechanistic Test for the Detection of Pathogenic aPL Antibodies; 4.5 New Technologies for the Detection of aPL; 4.6 Which aPL Should Be Tested in Patients With Suspicion of Having APS?; 4.7 Conclusions; Acknowledgements; References; 5 Genetic and Epigenetic Aspects of Antiphospholipid Syndrome; 5.1 HLA, APS, and aPL; 5.1.1 Family Studies.

Antiphospholipid Syndrome in Systemic Autoimmune Diseases, Second Edition provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations in both the thrombotic and non-thrombotic manifestations of this important disease. Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy, and memory loss, and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, and from psychiatry to orthopedics.

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