Includes bibliographical references and index.

Liver development: from endoderm to hepatocyte -- Functional development of the liver -- Mechanisms of bile formation and cholestasis -- The cholangiopathies -- Acute liver failure in children -- Cirrhosis and chronic liver failure -- Portal hypertension -- Laboratory assessment of liver function and injury in children -- Approach to the infant with cholestasis -- Medical and nutritional management of cholestasis in infants and children -- Neonatal hepatitis and congenital infections -- Biliary atresia and other disorders of the extrahepatic bile ducts -- Neonatal jaundice and disorders of bilirubin metabolism -- Familial hepatocellular cholestasis -- Alagille syndrome -- Diseases of the gallbladder in infancy, childhood, and adolescence -- Acute and chronic viral hepatitis -- Autoimmune hepatitis -- Sclerosing cholangitis -- Drug-induced liver disease -- Liver disease in immunodeficiencies -- Laboratory diagnosis of inborn errors of metabolism -- a₁-antitrypsin deficiency -- Cystic fibrosis liver disease -- Inborn errors of carbohydrate metabolism -- Copper metabolism and copper storage disorders -- Iron storage disorders -- Heme biosynthesis and the porphyrias -- Tyrosinemia -- The liver in lysosomal storage diseases -- Disorders of bile acid synthesis and metabolism: a metabolic basis for liver disease -- Inborn errors of mitochondrial fatty acid oxidation -- Mitochondrial hepatopathies -- Nonalcoholic fatty liver disease -- Peroxisomal diseases -- Urea cycle disorders -- Bacterial, parasitic, and fungal infections of the liver -- Systemic disease and the liver -- Fibrocystic liver disease -- Tumors of the liver -- Liver transplantation in children.