Intro -- Title Page -- Copyright Page -- Contents -- About the author -- Acknowledgements -- About the companion website -- Chapter 1 Introduction to respiratory medicine -- About the book -- Chapter 2 Embryology, anatomy, and physiology of the lung -- Introduction -- Development of the respiratory system -- Development of the lungs -- The respiratory tract -- Muscles of respiration and mechanical ventilation -- Structure of the lungs -- Blood supply of the lungs -- Nervous supply of the lungs -- Lymphatics of the lungs -- Control of breathing -- Central control -- Lung receptors and reflexes -- Chemoreceptors -- Transport of oxygen -- Transport of carbon dioxide -- The acid‐base balance -- Ventilation‐perfusion mismatch -- Lung defence -- Multiple choice questions -- Further Reading -- Chapter 3 Pharmacology of the lung -- Drugs and the lung -- Principles of drug deposition in lungs -- Inhaler devices -- Oxygen -- Inhaled drugs -- Drugs prescribed for smoking cessation -- Drugs that damage the lungs -- Multiple choice questions -- Further Reading -- Chapter 4 Common respiratory investigations -- Laboratory tests -- Imaging of the lung -- Lung function tests -- Exercise testing -- Sleep studies -- Cardiology investigations -- Invasive investigations -- Miscellaneous investigations -- Multiple choice questions -- Further Reading -- Chapter 5 Common presentations of respiratory disease -- Respiratory history -- Breathlessness -- Management of severe breathlessness -- Cough -- Haemoptysis -- Management of life‐threatening haemoptysis -- Chest pain -- Wheeze -- Hoarse voice -- Snoring -- Examination of the respiratory system -- Examination of the chest -- Pre‐operative respiratory assessment -- Post‐operative respiratory problems -- Respiratory assessment of an acutely ill patient -- Multiple choice questions -- Further Reading.

Chapter 6 Obstructive airways disease -- Introduction -- Asthma -- Definition -- Epidemiology -- Pathophysiology of asthma -- Clinical presentation -- Chronic obstructive pulmonary disease (COPD) -- ατ̔̈“«»«·1 Antitrypsin Deficiency -- Allergic bronchopulmonary aspergillosis (ABPA) -- Vocal cord dysfunction -- Hyperventilation syndrome (HV) -- Multiple choice questions -- Appendix 6.A Diagnosis of asthma -- Appendix 6.B Management of asthma -- Appendix 6.C Management of COPD -- Further Reading -- Chapter 7 Diffuse parenchymal lung disease -- Introduction -- Diagnosis of DPLD -- Investigations in a patient suspected of a DPLD -- Idiopathic interstitial pneumonias (IIP) -- Pathophysiology -- Idiopathic pulmonary fibrosis (IPF) -- Clinical presentation of IPF -- Investigations in IPF -- Management and prognosis in IPF -- Non‐specific interstitial pneumonia (NSIP) -- Clinical presentation of NSIP -- Investigations in NSIP -- Management of NSIP -- Prognosis in NSIP -- Cryptogenic organising pneumonia (COP) -- Desquamative interstitial pneumonia (DIP) -- Respiratory bronchiolitis interstitial lung disease (RB‐ILD) -- Lymphoid interstitial pneumonia (LIP) -- Acute interstitial pneumonia (AIP) -- Eosinophilic lung disease -- Sarcoidosis -- Clinical presentation of sarcoidosis -- Acute sarcoidosis (Löfgren's syndrome) -- Chronic sarcoidosis -- Multisystem sarcoidosis -- Investigations -- Radiology -- Blood tests -- Lung function test -- Histological diagnosis of sarcoidosis -- Other investigations -- Management and prognosis of sarcoidosis -- Hypersensitivity pneumonitis (HP) -- Acute hypersensitivity pneumonitis -- Sub‐acute hypersensitivity pneumonitis -- Chronic hypersensitivity pneumonitis -- Management of HP -- Prognosis of HP -- Lymphangioleiomyomatosis (LAM) -- Pulmonary Langerhans cell histiocytosis (PLCH) -- Pulmonary alveolar proteinosis (PAP).

Pulmonary amyloidosis -- Multiple choice questions -- Appendix 7.A Drugs that cause peripheral eosinophilia -- Further Reading -- Chapter 8 Respiratory infections -- Introduction -- Respiratory tract infections -- Pneumonia -- Viral pneumonia -- Bacterial pneumonia -- Community acquired pneumonia (CAP) -- Pathophysiology -- Diagnosis of CAP -- Microbiological diagnosis of CAP -- Radiological diagnosis of CAP -- Management of CAP -- Prognosis with CAP -- Hospital acquired pneumonia (HAP) -- Ventilator‐associated pneumonia -- Aspiration pneumonia -- Lipoid pneumonia -- Pulmonary infections in the immunocompromised -- Mycobacterium tuberculosis -- Epidemiology -- Pathogenesis of primary pulmonary tuberculosis -- Post‐primary tuberculosis -- Immunology -- Diagnosis -- Radiological diagnosis -- Microbiological and histological diagnosis -- Immunological diagnosis -- Management of MTB -- HIV and MTB -- Information to patients with TB -- Infectivity of tuberculosis -- Contact tracing -- Screening of immigrants -- Latent tuberculosis -- Prevention of Mycobacterium tuberculosis (MTB) -- Treatment of multi‐drug‐resistant tuberculosis (MDRTB) -- Pulmonary complications of mycobacterium tuberculosis -- Extra‐pulmonary tuberculosis -- Opportunistic (atypical) mycobacterium -- Multiple choice questions -- Further Reading -- Chapter 9 Lung cancer -- Introduction -- Epidemiology of lung cancer -- Aetiology of lung cancer -- Pathophysiology of lung cancer -- Clinical presentation of lung cancer -- Clinical signs of lung cancer -- Ectopic secretion of hormones in lung cancer -- Management of superior vena cava obstruction (SVCO) -- Management of a patient suspected of having a lung malignancy -- Clinical assessment of patient with suspected lung cancer -- Investigations for patients suspected of having lung cancer -- Histological diagnosis.

Classification of lung cancer -- Staging of NSCLC -- Staging of SCLC -- Management of lung cancer -- Surgery -- Essential investigations prior to surgery -- Fitness for surgery -- Post‐operative complications -- Follow‐up post‐surgery -- Radiotherapy -- Radical radiotherapy -- Palliative radiotherapy -- Chemotherapy -- Assessing fitness for chemotherapy -- Chemotherapy for NSCLC -- Chemotherapy for SCLC -- Palliative chemotherapy -- Side effects of chemotherapy -- Treatment response -- Targeted molecular therapy -- Palliative treatment -- Palliative procedures -- Communicating the diagnosis of lung cancer -- The lung multidisciplinary meeting -- Tracheal and laryngeal tumours -- Benign lung masses and solitary pulmonary nodules (SPN) -- Common causes of SPN and benign lung mass -- Cavitating lung lesions -- Carcinoid tumour -- Future developments -- Multiple choice questions -- Further Reading -- Chapter 10 Pleural disease -- Normal pleura and pleural fluid -- Pleural effusion -- Definition -- Aetiology of pleural effusion -- Clinical assessment of a patient presenting with a pleural effusion -- Diagnostic pathway for management of a unilateral pleural effusion -- Pleural Aspiration (Thoracocentesis) -- Pleural biopsy -- Differential diagnosis of a transudate -- Management of a transudate -- Differential diagnosis of an exudate -- Management of malignant pleural effusion -- Pleural infection and empyema -- Definitions -- Aetiology of pleural infection -- Pathophysiology of pleural infection -- Pneumothorax -- Definition -- Primary spontaneous pneumothorax (PSP) -- Secondary pneumothorax (SP) -- Clinical presentation of pneumothorax -- Investigations for a pneumothorax -- Classification of pneumothorax -- Management of pneumothorax -- Management of primary spontaneous pneumothorax (PSP) -- Intercostal chest drain insertion for pneumothorax.

Management of secondary pneumothorax (SP) -- Management of patients with a chest drain for pneumothorax -- Complications of chest drain for pneumothorax -- Surgery for persistent pneumothorax -- Traumatic pneumothorax -- Tension pneumothorax -- Management of tension pneumothorax -- Recurrent pneumothorax -- Asbestos‐related pleural disease -- Benign pleural plaque -- Diffuse pleural thickening -- Benign asbestos‐related pleural effusion -- Mesothelioma -- Aetiology of mesothelioma -- Pathophysiology of mesothelioma -- Investigations in the diagnosis of malignant mesothelioma -- Pleural biopsy -- Pathological types of malignant mesothelioma -- Management of malignant mesothelioma -- Palliative care -- Chemotherapy -- Surgery -- Compensation -- Multiple choice questions -- Appendix 10.A Analysis of pleural fluid -- Biochemistry -- Microbiology -- Cytology -- pH -- Haematocrit -- Appendix 10.B Compensation for asbestos‐related disease -- Further Reading -- Chapter 11 Pulmonary embolus, pulmonary hypertension, and vasculitides -- Introduction -- Pulmonary embolism -- Acute pulmonary embolus -- Diagnosis of pulmonary embolus -- Investigations in the diagnosis of pulmonary embolus -- Imaging to confirm a diagnosis of PE -- Management of acute pulmonary embolus -- Anticoagulation -- Oral anticoagulation -- Duration of anticoagulation -- Inferior vena cava filter -- Management of massive life‐threatening pulmonary embolus -- Prognosis after acute PE -- Recurrent pulmonary emboli -- Chronic pulmonary emboli -- Pulmonary hypertension -- Classification of pulmonary hypertension -- Group 1: Pulmonary Arterial Hypertension -- Group 2: Pulmonary hypertension secondary to left heart disease -- Group 3: Pulmonary hypertension secondary to lung disease -- Group 4: Pulmonary hypertension secondary to chronic thromboembolic disease (CTEPH).

Group 5: Multifactorial pulmonary hypertension.

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