Includes bibliographical references.

Introduction -- Committee approach -- E-cigarette devices, uses and exposures -- Nicotine -- Toxicology of e-cigarette constituents -- Research needs: e-cigarette devices, constituents and exposures -- Modes of action -- Dependence and abuse liability -- Cardiovascular disease -- Cancers -- Respiratory diseases -- Oral diseases -- Developmental and reproductive effects -- Injuries and poisonings -- Research needs: effects of e-cigarettes on health -- Combustible tobacco cigarette smoking among youth and young adults -- Smoking cessation among adults -- Harm reduction -- Modeling of e-cigarette use -- Research needs: public health implications of e-cigarettes -- Concluding observations -- Appendixes.

"Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research." --Publisher's description.