Cover title.

Includes bibliographical references.

Cardiovascular defense challenges at the basic, clinical, and population levels -- Plaque neovascularization : defense mechanisms, betrayal, or a war in progress -- LDL-cholesterol versus HDL-cholesterol in the atherosclerotic plaque : inflammatory resolution versus thrombotic chaos -- Evolving role of molecular imaging for new understanding : targeting myofibroblasts to predict remodeling -- Molecular targets in heart failure gene therapy : current controversies and translational perspectives -- Engineered arterial models to correlate blood flow to tissue biological response -- A bird's-eye view of cell therapy and tissue engineering for cardiac regeneration -- Umbilical cord blood for cardiovascular cell therapy : from promise to fact -- Heart repair : from natural mechanisms of cardiomyocyte production to the design of new cardiac therapies -- Energy metabolism plasticity enables stemness programs -- The future : therapy of myocardial protection -- The links between complex coronary disease, cerebrovascular disease, and degenerative brain disease -- Optimal lipid targets for the new era of cardiovascular prevention -- Controversies in blood pressure goal guidelines and masked hypertension -- Evolving diagnostic and prognostic imaging of the various cardiomyopathies -- The evolving landscape of quality measurement for heart failure -- Atrial fibrillation, stroke, and quality of life -- Transcatheter aortic valve implantation and cerebrovascular events : the current state of the art -- Are we ignoring the dilated thoracic aorta?

"This Annals volume stems from the two-day conference "Evolving Challenges in Promoting Cardiovascular Health" sponsored by the New York Academy of Sciences, "la Caixa" Foundation, and the International Center for Scientific Debate (ICSD), which took place November 4-5, 2011 in Barcelona, Spain. Leading and emerging investigators working on the fields of cardiology, vascular disease, inflammation, metabolic disorders, hematology, imaging, regenerative medicine, stem cell research, epidemiology, and nutrition, among others, address novel issues, current challenges, and future directions in the prevention, treatment, and management of the evolving global epidemic of cardiovascular disease. The papers in this volume explore the promotion of cardiovascular health through molecular biology, clinical pathophysiology, and population research"--Publisher's description.