The antibody molecule : from antitoxins to therapeutic antibodies / by Anthony R. Rees, Principal, Rees Consulting AB, Uppsala, Sweden, and Professor Emeritus, University of Bath, UK.
By: Rees, Anthony R [author.].
Publisher: Oxford, United Kingdom ; New York, NY, United States of America : Oxford University Press, 2015Edition: First edition.Description: xii, 364 pages : illustrations ; 25 cm.Content type: still image | text Media type: unmediated Carrier type: volumeISBN: 9780199646579.Subject(s): Immunoglobulins | Immunology -- History | Allergy and Immunology -- History | Antibodies | Immunoglobulins | Immunoglobulins | ImmunologyGenre/Form: History. | Print books.Online resources: Table of contents only | Contributor biographical information | Publisher descriptionCurrent location | Call number | Status | Date due | Barcode | Item holds |
---|---|---|---|---|---|
On Shelf | QR186.7 .R44 2015 (Browse shelf) | Available | AU0000000004990 |
Includes bibliographical references and indexes.
Antibody pre-history: the emergence of empirical immunology -- Pre-molecular immunology: the dawn of mechanism -- Structural chemistry: locks, keys, and colloids -- The foundations of antibody-antigen recognition emerge -- The cellular reformation -- The molecular path unfolds -- Uncovering the origins of antibody diversity -- Immunoglobulin constant regions -- Effector functions of constant regions -- Transmission and catabolism of IgG -- The structural context of antibody diversity -- Monoclonal antibodies and the mechanisms of hypermutation -- Antibody structure prediction and development of humanization strategies -- Antibody engineering: improving on natural immunity -- Therapeutic antibodies: case study I: prevention of respiratory syncytial virus illness -- Therapeutic antibodies: case study II: targeting breast cancer -- Antibodies: the therapeutic future.