Turner, J. Rick. <br/><br/>
Integrated cardiac safety  assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance /  [electronic resource] : 
J. Rick Turner, Todd A. Durham. 
 - Hoboken, N.J. :  John Wiley & Sons,  c2009. 
 - xxviii, 470 p. :  ill. 
<br/><br/>Includes bibliographical references (p. 397-455) and index. 
<br/><br/>The importance of cardiac safety assessments -- The biological basis of adverse drug reactions -- Cardiac structure and function -- Cardiac pathophysiology and disease -- Drug discovery and drug design -- Nonclinical development -- The thorough QT/QTc trial -- General safety assessments -- Therapeutic use trials and meta-analyses -- Assessment methodologies in nonexperimental postmarketing surveillance -- Postmarketing proarrhythmic cardiac safety assessments -- Generalized cardiac safety -- Medication errors, adherence, and concordance -- Future directions in drug safety. 
<br/><br/><br/>Electronic reproduction. <br/>Palo Alto, Calif. : <br/>ebrary, <br/>2013. <br/>Available via World Wide Web. <br/>Access may be limited to ebrary affiliated libraries. 
<br/><br/><label>ISBN: </label>0470229640 (cloth) 9780470229644 (cloth) 
<br/><br/><label>LCCN: </label>
<br/><br/><label>Nat. Bib. Agency Control No.: </label> DNLM 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Cardiovascular toxicology.<br/>Drugs--Safety measures.<br/>Drugs--Side effects--Testing.<br/>Heart--Effect of drugs on.
<br/><br/><label>Index Terms--Genre/Form: </label><br/>Electronic books.
<br/><br/><label>LC Class. No.: </label>RC677  / .T87 2009eb 
<br/><br/><label>Dewey Class. No.: </label>616.1/23061