TY - BOOK AU - Monastyrsky,Michail Ilych ED - SpringerLink (Online service) TI - Topology in Molecular Biology T2 - Biological and Medical Physics, Biomedical Engineering, SN - 9783540498582 AV - QH505 U1 - 571.4 23 PY - 2007/// CY - Berlin, Heidelberg PB - Springer Berlin Heidelberg KW - Physics KW - Molecular biology KW - Bioinformatics KW - Biophysics KW - Biological physics KW - Biophysics and Biological Physics KW - Molecular Medicine KW - Electronic books KW - local N1 - Topology in Biology: From DNA Mechanics to Enzymology -- Monte Carlo Simulation of DNA Topological Properties -- Dynamics of DNA Supercoiling -- From Tangle Fractions to DNA -- Linear Behavior of the Writhe Versus the Number of Crossings in Rational Knots and Links -- Combinatories and Topology of the ?-Sandwich and ?-Barrel Proteins -- The Structure of Collagen -- Euler Characteristic, Dehn–Sommerville Characteristics, and Their Applications -- Hopf Fibration and Its Applications -- Multi-Valued Functionals, One-Forms and Deformed de Rham Complex -- The Spectral Geometry of Riemann Surfaces N2 - The book presents a class of new results in molecular biology for which topological methods and ideas are important. These include: the large-scale conformation properties of DNA; computational methods (Monte Carlo) allowing the simulation of large-scale properties of DNA; the tangle model of DNA recombination and other applications of Knot theory; dynamics of supercoiled DNA and biocatalitic properties of DNA; the structure of proteins; and other very recent problems in molecular biology. The text also provides a short course of modern topology intended for the broad audience of biologists and physicists. The authors are renowned specialists in their fields and some of the new results presented here are documented for the first time in monographic form UR - http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-3-540-49858-2 ER -