TY  - BOOK
AU  - Boelens,Jaap Jan
AU  - Wynn,Robert
ED  - SpringerLink (Online service)
TI  - Stem Cell Therapy in Lysosomal Storage Diseases
T2  - Stem Cell Biology and Regenerative Medicine,
SN  - 9781461483571
AV  - QH588.S83 
U1  - 571.6 23
PY  - 2013///
CY  - New York, NY
PB  - Springer New York, Imprint: Humana Press
KW  - Life sciences
KW  - Human genetics
KW  - Cell biology
KW  - Stem cells
KW  - Life Sciences
KW  - Stem Cells
KW  - Cell Biology
KW  - Human Genetics
KW  - Electronic books
KW  - local
N1  - 1. Lysosomal Diseases and Therapeutic Options: An Overview -- 2. Alternative Treatment Options: Enzyme Replacement and Small Molecule Therapies -- 3. Hematopoietic Cell Transplantation in Inborn Errors of Metabolism -- 4. Allogeneic Hematopoietic Stem Cell Transplantation in Lysosomal Storage Disorders: Long Term Neurodevelopmental and Somatic Outcome -- 5. Hematopoietic Stem Cell Gene Therapy for Lysosomal Storage Disorders: Expected Benefits and Limitations -- 6. Alternative Future Therapies for Lysosomal Storage Diseases: Embryonic Stem Cell- and Induced Pluripotent Stem Cell Therapy -- 7. New Directions and Conclusions
N2  - Stem Cell therapy for lysosomal diseases (LSDs) is developing rapidly. This volume discusses the history, current practice and future perspectives of stem cells in inborn errors of metabolism (IEM) and provides an international perspective on progress, limitations, and future directions (e.g. gene therapy, iPS, ES) in the field. Beginning with an overview of these diseases, the book covers the breadth of this topic from treatment options, bone marrow transplantation, and alternative treatment options, through long-term outcomes and future perspectives
UR  - http://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-1-4614-8357-1
ER  -