TY - BOOK AU - Strachan,T. AU - Goodship,J. AU - Chinnery,Patrick F. TI - Genetics and genomics in medicine SN - 9780815344803 (paperback : alk. paper) AV - RB155.5 .S77 2015 U1 - 616/.042 23 PY - 2015///] CY - New York PB - Garland Science/Taylor & Francis Group KW - Genetic Phenomena KW - Genetic Diseases, Inborn KW - therapy KW - Genomics KW - Individualized Medicine KW - local KW - Print books N1 - Includes bibliographical references and index N2 - "Genetics and Genomics in Medicine is a new textbook written for undergraduate and graduate students, as well as medical researchers, which explains the science behind the uses of genetics and genomics in medicine today. It is not just about rare inherited and chromosomal disorders, but how genetics affects the whole spectrum of human health and disease. DNA technologies are explained, with emphasis on the modern techniques that have revolutionized the use of genetic information in medicine and are indicating the role of genetics in common complex diseases. The detailed, integrative coverage of genetic approaches to treatment and prevention includes pharmacogenomics and the prospects for personalized medicine. Cancers are essentially genetic diseases and are given a dedicated chapter that includes new insights from cancer genome sequencing. Clinical disorders are covered throughout and there are extensive end-of-chapter questions and problems"-- ER -