TY - BOOK AU - Maryanoff,B.E. AU - Maryanoff,C.A. ED - ScienceDirect eBooks. TI - Advances in medicinal chemistry AV - RS400 .A35eb v. 3 PY - 1995/// KW - Pharmaceutical chemistry KW - fast KW - Electronic books KW - local N2 - Volume 3 of Advances in Medicinal Chemistry is comprised of four chapters on diverse aspects of medicinal chemistry. Chapter 1 presents an account of a research program which was started to discover a novel antipsychotic agent with minimal side effects for the treatment, principally, of schizophrenia. Chapter 2 relates an account on the discovery of novel antithrombotic drugs based on the RGD motif through a rational design approach. Chapter 3 presents the medicinal chemistry and preclinical development surrounding sertraline, a very important serotonin reuptake drug for the treatment of endogenous depression. Finally, Chapter 4 gives a summary of a series of boronic acid-based immunosuppressants that operate via inhibition of dipeptidypeptidase IV UR - http://ezproxy.alfaisal.edu/login?url=https://www.sciencedirect.com/science/bookseries/10675698/3 ER -