TY  - BOOK
AU  - Reitz,Allen Bernard
AU  - Dax,S.L.
ED  - ScienceDirect eBooks.
TI  - Advances in medicinal chemistry
SN  - 1281019445
AV  - RS400 .A35eb v. 5
PY  - 2000///
KW  - Pharmaceutical chemistry
KW  - fast
KW  - Electronic books
KW  - local
N1  - Preface. Immunophilins: the next generation. Discovery of ABT-594 and related neuronal nicotinic acetylcholine receptor modulators as analgesic agents: medicinal chemistry and biology. Discovery and preclinical evaluation of novel dopamine partial agonists as antipsychotic agents. Nonpeptide inhibitors of HIV protease
N2  - Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed
UR  - http://ezproxy.alfaisal.edu/login?url=https://www.sciencedirect.com/science/bookseries/10675698/5
ER  -