Protein mass spectrometry /
edited by Julian P. Whitelegge.
- 1st ed.
- Amsterdam ; Boston : Elsevier, 2009.
- 1 online resource (xxxii, 518 pages, [12] leaves of plates) : illustrations (some color).
- Wilson and Wilson's comprehensive analytical chemistry, v. 52 0166-526X ; .
- Comprehensive analytical chemistry ; v. 52. .
Includes bibliographical references and index.
Foreword -- Chapter 1. An Introduction to the Basic Principles and Concepts of Mass Spectrometry -- Kym Faull, Alek N. Dooley, Frederic Halgand, Lorelei D. Shoemaker, Andrew J. Norris, Christopher M. Ryan, Arthur Laganowsky, Jodie V. Johnson and Jonathan E. Katz -- Chapter 2. Charaterization of protein conformation and dynamics with ESI MS -- Igor Kaltashov and Wendell P. Griffith -- Chapter 3. An Introduction to Ion Mobility and Mass Spectrometry of Non-Covalent Protein Complexes Summer Bernstein, and Michael Bowers -- Chapter 4. Study of protein structure using hydrogen-deuterium exchange -- Jennifer L. Mitchell and John R. Engen -- Chapter 5. Stopped flow analysis with MS -- Lars Konermann, Jingxi Pan, and Derek J. Wilson -- Chapter 6. SUPREX; Stability of Unpurified Proteins by Rates of H/D Exchange -- Michael C. Fitzgerald, Liangjie Tang, and Erin D. Hopper -- Chapter 7. Microsecond time-scale hydroxyl radical profiling of solvent-accessible protein residues -- David Hambly and Michael Gross -- Chapter 8. Intact Protein Mass Measurements and Top-Down Mass Spectrometry: Application to Integral Membrane Proteins. -- Julian P. Whitelegge -- Chapter 9. Analysis of dynamic membrane protein structure-function relationships using chemical modification techniques and mass spectrometry -- Adam B. Weinglass, -- Chapter 10. Shotgun approaches to membrane protein structure and topology -- Anna E. Speers and Christine Wu -- Chapter 11. Covalent trapping of protein interactions in complex systems -- Rasanjala Weerasekera, Tujin Shi and Gerold Schmitt-Ulms -- Chapter 12. Phosphoproteomics -- Martin R. Larsen and Phillip J. Robinson -- Chapter 13. Detection of tyrosine phosphorylation sites by mass spectrometry -- Guoan Zhang, Chongfeng Xu and Thomas A. Neubert -- Chapter 14. Histidine Phosphorylation -- Xin-Lin Zu, Paul G. Besant and Paul V. Attwood -- Chapter 15. O-glcnac modification of proteins -- Robert J. Chalkley, Lance Wells and Keith Vosseller -- Chapter 16. Analysis of Deamidation in Proteins -- Jason J. Cournoyer and Peter B. O'Connor -- Chapter 17. Quantitative Proteomics -- Silke Oeljeklaus, Jon Barbour and Bettina Warscheid -- Chapter 18. Multiplexed Quantitative Proteomics using Mass Spectrometry -- Philip L. Ross, Xunming Chen, Esteban Toro, Leticia Britos, Lucy Shapiro, Darryl Pappin -- Chapter 19. Large-scale subcellular localization of proteins by protein correlation profiling. -- Leonard J. Foster -- Chapter 20. Accuracy of Quantitation from Full and Partial Metabolic Labeling Experiments -- Edward L. Huttlin, Adrian D. Hegeman and Michael R. Sussman, Ph. D.
This book is designed to be a central text for young graduate students interested in mass spectrometry as it relates to study of protein structure and function as well as proteomics. It is a definite must have work for: - libraries at academic institutions with Master and Graduate programs in Biochemistry, Molecular Biology, Structural Biology and Proteomics; - individual laboratories with interests covering these areas; and - libraries and individual laboratories in the pharmaceutical and biotechnology industries. . serves as an essential reference to those working in the field . incorporates the contributions of prominent experts . features comprehensive coverage and a logical structure.
9780080932033 0080932037
Proteins--Spectra. Mass spectrometry. Proteomics. SCIENCE--Life Sciences--Biochemistry. Mass spectrometry. Proteins--Spectra. Proteomics. Massenspektrometrie. Proteine. Proteins--analysis. Mass Spectrometry.