Epigenetic technological applications / 
edited by Y. George Zheng. 
 -  [2015] 
 - 1 online resource. 
 - Translational epigenetics series .
 - Translational epigenetics series. .
<br/><br/>Includes bibliographical references and index. 
<br/><br/>The state of the art of epigenetic technologies -- Technologies for the measurement and mapping of genomic 5-methylcytosine and 5-hydroxymethylcytosine -- High-throughput sequencing-based mapping of cytosine modifications -- Application of mass spectrometry in translational epigenetics -- Techniques analyzing chromatin modifications at specific single loci -- Comprehensive analysis of mammalian linker-histone variants and their mutants -- Crystallography-based mechanistic insights into epigenetic regulation -- Chemical and genetic approaches to study histone modifications -- Peptide microarrays for profiling of epigenetic targets -- Current methods for methylome profiling -- Bioinformatics and biostatistics in mining epigenetic disease markers and targets -- Computational modeling to elucidate molecular mechanisms of epigenetic memory -- DNA methyltransferase inhibitors for cancer therapy -- Histone acetyltransferases: enzymes, assays, and inhibitors -- In vitro histone deacetylase activity screening: making a case for better assays -- Enzymatic assays of histone methyltransferase enzymes -- Histone methyltransferase inhibitors for cancer therapy -- Discovery of histone demethylase inhibitors -- Histone demethylases: background, purification, and detection -- Animal model study of epigenetic inhibitors -- Index. 
<br/><br/><label>ISBN: </label>9780128013274 0128013273 0128010800 9780128010808 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Epigenetics.<br/>SCIENCE / Life Sciences / Biochemistry<br/>Epigenetics.<br/>Genetic Therapy.<br/>Acetylation.<br/>DNA Methylation--genetics.<br/>Epigenomics.<br/>Genetic Predisposition to Disease.
<br/><br/><label>Index Terms--Genre/Form: </label><br/>Electronic books.
<br/><br/><label>LC Class. No.: </label>QH450