TY - BOOK AU - Arnon,R. AU - Miller,Ariel ED - ScienceDirect eBooks. TI - Translational neuroimmunology in multiple sclerosis: from disease mechanisms to clinical applications SN - 9780128020074 AV - RC377 PY - 2016///] CY - Amsterdam PB - Academic Press is an imprint Elsevier KW - Multiple sclerosis KW - Neuroimmunology KW - HEALTH & FITNESS / Diseases / General KW - bisacsh KW - MEDICAL / Clinical Medicine KW - MEDICAL / Diseases KW - MEDICAL / Evidence-Based Medicine KW - MEDICAL / Internal Medicine KW - fast KW - Electronic books KW - local N1 - Includes bibliographical references and index N2 - Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon-such as neuroprotective strategies, stem cells, and repair promotion-are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development UR - http://ezproxy.alfaisal.edu/login?url=https://www.sciencedirect.com/science/book/9780128019146 ER -