02367cam a2200409 i 4500001001300000003000700013005001700020008004100037010001700078020002900095020002600124020003500150020003000185035003900215040004800254042000800302050002000310100003300330245011700363260001300480264003900493300002900532336002700561337002900588338002800617504005100645520098000696650003701676650002001713650003301733650003101766650004701797650002601844650004301870650002001913655002401933ocn958798220US-DLC20190317110514.0170113s2017    nyu      b    001 0 eng    a  2017001183  z9780465097906qhardcover  z0465097901qhardcover  z9780465097913qelectronic book  a9781541644144 (softcover)  a(OCoLC)958798220z(OCoLC)978270365  aDLCbengerdacDLCdOCLCFdOCLCQdOCLCOdAU  apcc00aR852b.H37 20171 aHarris, Richard F.,eauthor.10aRigor mortis :bhow sloppy science creates worthless cures, crushes hope, and wastes billions /cRichard Harris.  c©2017.  1aNew York :bBasic Books,c©2017.   avii, 278 pages ;c22 cm.  atextbtxt2rdacontent.  aunmediatedbn2rdamedia.  avolumebnc2rdacarrier.  aIncludes bibliographical references and index.  a"American taxpayers spend $30 billion annually funding biomedical research. By some estimates, half of the results from these studies can't be replicated elsewhere-the science is simply wrong. Often, research institutes and academia emphasize publishing results over getting the right answers, incentivizing poor experimental design, improper methods, and sloppy statistics. Bad science doesn't just hold back medical progress, it can sign the equivalent of a death sentence. How are those with breast cancer helped when the cell on which 900 papers are based turns out not to be a breast cancer cell at all? How effective could a new treatment for ALS be when it failed to cure even the mice it was initially tested on? In Rigor Mortis, award-winning science journalist Richard F. Harris reveals these urgent issues with vivid anecdotes, personal stories, and interviews with the nation's top biomedical researchers. We need to fix our dysfunctional biomedical system-now"-- 0aMedicinexResearchxMethodology. 0aMedical ethics. 7aMEDICALxResearch.2bisacsh. 7aMEDICALxEthics.2bisacsh. 7aSCIENCExResearch & Methodology.2bisacsh. 7aMedical ethics.2fast 7aMedicinexResearchxMethodology.2fast 4aMedical ethics. 02localaPrint books.