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  <titleInfo>
    <nonSort>The </nonSort>
    <title>role of general clinical research centers in clinical trials</title>
    <subTitle>a characterization with recommendations</subTitle>
  </titleInfo>
  <name type="personal">
    <namePart>Hopwood, Marsha D.</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
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    <role>
      <roleTerm type="text">author.</roleTerm>
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  </name>
  <name type="personal">
    <namePart>Mabry, John C.</namePart>
    <namePart type="date">1951-</namePart>
    <role>
      <roleTerm type="text">author.</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Sibley, W. L.</namePart>
    <role>
      <roleTerm type="text">author.</roleTerm>
    </role>
  </name>
  <name type="corporate">
    <namePart>Rand Corporation</namePart>
  </name>
  <name type="corporate">
    <namePart>National Institutes of Health (U.S.)</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">cau</placeTerm>
    </place>
    <dateIssued encoding="marc">1980</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marcform">print</form>
    <extent>xi, 51 pages : illustrations ; 28 cm</extent>
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  <abstract>Reports the results of the second year of a two-year project to evaluate the role of NIH-supported General Clinical Research Centers (GCRCs) in clinical trials, with emphasis on information processing.  GCRCs provide personnel and facility resources to support clinical research (including trials).  Based on interviews with about 130 investigators and 75 support staff members, the authors recommended that the GCRCs should provide research data coordinators to support clinical trials; make biomedical scientists available in the GCRCs on a regular but limited consulting basis; augment the functional capabilities of the CLINFO data management and analysis system to include analysis of covariance, improved data editing, document tracking, sample size determination and randomization; provide a computerized nutrient database and diet calculation program for GCRC dietitians; provide fiscal management and word processing computer programs for GCRC administrative coordinators; and explore methods to help investigators increase their expertise in research methodology, statistics, and information processing.</abstract>
  <note type="statement of responsibility">Marsha D. Hopwood, John C. Mabry, William L. Sibley.</note>
  <note>"November 1980."</note>
  <note>Includes bibliographical references (p. 51).</note>
  <note>Also available on the internet via WWW in PDF format.</note>
  <subject>
    <geographicCode authority="marcgac">n-us---</geographicCode>
  </subject>
  <subject authority="lcsh">
    <topic>CLINFO (Computer system)</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Clinical trials</topic>
    <geographic>United States</geographic>
  </subject>
  <subject authority="lcsh">
    <topic>Medicine</topic>
    <topic>Research</topic>
    <geographic>United States</geographic>
  </subject>
  <classification authority="lcc">R854.U5 H67 1980</classification>
  <identifier type="isbn">0833002899</identifier>
  <identifier type="lccn">80028740</identifier>
  <identifier type="stock number"/>
  <identifier type="uri">http://www.rand.org/pubs/reports/R2669/</identifier>
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    <url displayLabel="Online Access">http://www.rand.org/pubs/reports/R2669/</url>
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    <recordCreationDate encoding="marc">920212</recordCreationDate>
    <recordIdentifier source="RAND">rnd000000000047134</recordIdentifier>
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