Derived from the critically acclaimed reference PET: Molecular Imaging and Its Biological Applications, edited by Michael E. Phelps, Ph.D., this handbook provides a clear and concise introduction to the physics and instrumentation aspects of PET imaging. Comprised of select material from the parent volume, this book is gives the reader a solid understanding of PET fundamentals, including how PET data are collected and formed into an image. Other topics include basic physics, detector technology used in modern PET scanners, data acquisition, 3-D reconstruction, and methods for evaluating the performance of PET systems. A variety of modern PET imaging systems is discussed, ranging from those designed for clinical services and research to those used in small-animal imaging. As the importance of PET imaging in nuclear medicine and radiology grows, the need for a reliable resource increases. PET: Physics, Instrumentation, and Scanners is a handy guide to this important field.