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Rb and Tumorigenesis [electronic resource] / by Maurizio Fanciulli.

By: Contributor(s): Series: Molecular Biology Intelligence UnitPublisher: Boston, MA : Springer US, 2006Description: IX, 121 p. online resourceContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9780387339153
Subject(s): Genre/Form: Additional physical formats: Printed edition:: No titleDDC classification:
  • 571.6 23
LOC classification:
  • QH573-671
Online resources:
Contents:
RB as a Positive Transcriptional Regulator during Epithelial Differentiation -- pRb in the Differentiation of Normal and Neoplastic Cells -- Regulation of DNA Replication by the Retinoblastoma Tumor Suppressor Protein -- New Insights into Transcriptional Regulation by Rb -- Regulation of Rb Function by Noncyclin Dependent Kinases -- Diverse Regulatory Functions of the E2F Family of Transcription Factors -- Regulation of E2F-Responsive Genes through Histone Modifications -- Emerging Roles for the Retinoblastoma Gene Family -- Rb and Cellular Differentiation.
In: Springer eBooksSummary: Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle.
Item type: eBooks
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RB as a Positive Transcriptional Regulator during Epithelial Differentiation -- pRb in the Differentiation of Normal and Neoplastic Cells -- Regulation of DNA Replication by the Retinoblastoma Tumor Suppressor Protein -- New Insights into Transcriptional Regulation by Rb -- Regulation of Rb Function by Noncyclin Dependent Kinases -- Diverse Regulatory Functions of the E2F Family of Transcription Factors -- Regulation of E2F-Responsive Genes through Histone Modifications -- Emerging Roles for the Retinoblastoma Gene Family -- Rb and Cellular Differentiation.

Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle.

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