Includes bibliographical references and indexes.

Print version record.

Hormones have a manifold impact upon growth and metabolism. This book focuses upon the molecular biology of fish hormones and their regulation. Chapters dealing with gonadotropin, corticotropin, vasotocin, isotocin, somatolactin, and other hormones are written by an international team of fish physiologists and endocrinologists. In addition, there are chapters that survey a growing literature on the ways hormones are regulated both in terms of their actions and in terms of the gene transcription that leads to their formation. The first two sections of the book covers brain and pituitary hormones and the latter two sections are devoted to other hormones and their regulation. As more and more endocrinologists and physiologists seek to use hormones that are inexpensive, provide for more facile experimental replication, and are less subject to cumbersome regulation, they will turn to the sorts of fish models reviewed in this book.

Front Cover; Fish Physiology; Copyright Page; Contents; Contributors; Preface; Contents of Other Volumes; Part I. Brain Hormones; Chapter 1. Molecular Evolution of Growth Hormone-Releasing Hormone and Gonadotropin-Releasing Hormone; I. Introduction; II. GHRH-PACAP; III. Gonadotropin-Releasing Hormone; IV. Intertwining of Function in the GnRH and GHRH Families; References; Chapter 2. Corticotropin-Releasing Factors Acting on the Fish Pituitary: Experimental and Molecular Analysis; I. Introduction; II. ACTH-Releasing Peptides and Their Receptors.

III. CRF, Its Protein Precursors, cDNAs, and GenesIV. Evolutionary Considerations for CRF-UI; References; Chapter 3. Expression of the Vasotocin and Isotocin Gene Family in Fish; I. Introduction; II. Genes, cDNAs, and Precursors; III. Divergence of VT and IT Gene Expression; IV. VT and IT Gene Expression in Osmotic Adaptation; V. Conclusion; References; Part II. Pituitary Hormones; Chapter 4. Control of Teleost Gonadotropin Gene Expression; I. Introduction; II. Duality of Teleost Gonadotropins; III. Genomic Organization of Teleost Gonadotropins; IV. Control of Gonadotropin Gene Expression.

V. ConclusionReferences; Chapter 5. The Somatolactin Gene; I. Somatolactin; II. Somatolactin Gene; III. Regulation of Somatolactin Gene Expression; IV. Conclusion; References; Chapter 6. Structure and Evolution of Fish Growth Hormone and Insulinlike Growth Factor Genes; I. Introduction; II. Conserved Domains of Fish Growth Hormones; III. Conserved Domains of Fish Prolactins and Somatolactins; IV. Genomic Organization of Fish GH, PRL, and SL Genes; V. Ancestral Gene of the Fish Growth Hormone Gene Family; VI. A Functional Model of Fish Growth Hormone Gene Family.

VII. Fish IGF I and IGF II mRNAsVIII. Age- and Tissue-Specific Levels of Five IGF mRNAs; IX. Concluding Remarks; References; Part III. Other Hormones; 7. Structure and Expression of Insulinlike Growth Factor Genes in Fish; I. Introduction; II. IGF Activity in Fish; III. Cloning of Fish IGF cDNAs and Genes; IV. Expression and Regulation of IGF; V. Summary and Perspective; References; 8. Molecular Aspects of Pancreatic Peptides; I. Introduction; II. Insulin; III. Glucagon and Glucagonlike Peptide; IV. Somatostatin; V. Pancreatic Polypeptide and Related Peptides; References.

Chapter 9. The Molecular Biology of the Corpuscles of Stannius and Regulation of Stanniocalcin Gene ExpressionI. Introduction; II. A Brief History of Discovery; III. Molecular Cloning of Eel and Salmon Stanniocalcin; IV. Structural Comparisons of Eel and Salmon Stanniocalcin; V. Studies on Tissue-Specific Expression of the Stanniocalcin Gene; VI. Localization of Stanniocalcin mRNA in CS Cells by in Situ Hybridization; VII. Calcium Regulation of Stanniocalcin Cell Activity; VIII. Conclusions; References; Part IV. Hormone Regulation.

Elsevier ScienceDirect All Books