Hirschsprung’s Disease: A Historical Perspective — 1691–2005 -- Development of the Enteric Nervous System -- Functional Anatomy of the Enteric Nervous System -- Animal Models of Aganglionosis -- The Molecular Genetics of Hirschsprung’s Disease -- Normal Colonic Motor Function and Relevant Structure -- Pathophysiology of Hirschsprung’s Disease -- Hirschsprung’s Disease: Clinical Features -- Congenital Anomalies and Genetic Associations in Hirschsprung’s Disease -- Enterocolitis Complicating Hirschsprung’s Disease -- Diagnosis of Hirschsprung’s Disease and Allied Disorders -- Functional Diagnosis -- Histopathological Diagnosis and Differential Diagnosis of Hirschsprung’s Disease -- NADPH-Diaphorase Histochemistry -- Immunohistochemical Studies -- Electron Microscopic Studies of Hirschsprung’s Disease -- Intestinal Neuronal Malformations (IND): Clinical Experience and Treatment -- Neurocristopathies and Particular Associations with Hirschsprung’s Disease -- Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome -- Degenerative Hollow Visceral Myopathy Mimicking Hirschsprung’s Disease -- Adynamic Bowel Syndrome -- Anal Sphincter Achalasia and Ultrashort Hirschsprung’s Disease -- Laparoscopically Assisted Anorectal Pull-Through -- Swenson’s Procedure -- Soave’s Extramucosal Endorectal Pull-Through Procedure -- Rehbein’s Procedure (Deep Anterior Resection) -- Transanal Pull-Through for Hirschsprung’s Disease -- Duhamel’s Procedure -- Early and Late Complications Following Operative Repair of Hirschsprung’s Disease -- Long-Term Results and Quality of Life After Treatment of Hirschsprung’s Disease and Allied Disorders -- Laparoscopic-Assisted Transanal Pull-Through for Hirschsprung’s Disease.

Hirschsprung's Disease and Allied Disorders is the third edition of a comprehensive study of the neuronal disorders of the lower gastrointestinal tract in children. Important new studies and progress in research on bowel motility and motility disorders are covered in detail as well as new aspects concerning the embryology, functional anatomy of the enteric nervous system. In particular new insights have been received from the studies in the genetics of Hirschsprung's disease. Special emphasis is laid on new surgical techniques, especially on the laparoscopic approach in combination with Soave's or Duhamel's technique.