With screening and selection of biocatalysts being undervalued in Europe in comparison with USA and especially Japan, the working parties "Applied Biocatalysis" and "Microbial Physiology" of the European Federation of Biotechnology decided to organise an international symposium entitled "New Frontiers in Screening for Microbial Biocatalysts". Novel screening techniques, microbial biodiversity, microbial physiology and molecular genetics were discussed to give better insights into possibilities and limitations of obtaining biocatalysts from nature. These proceedings provide a comprehensive overview of the present state-of-the-art in the field of biocatalysts screening.

Selected papers: Oral Presentations. General introduction to biocatalysis and screening (K. Kieslich). A Japanese screening approach: selection of an opine dehydrogenase and alkaline D-peptidase (Y. Asano). The enormous diversity and biotechnological potential of naturally occurring bacteria (E. Stackebrandt). Fluorescence screening for lipolytic enzymes (A. Hermetter <IT>et al.</IT>). Filtration and separation materials for analytical purposes (R.G. Hood). Screening for inhibitors of human brain myo-insitol monophosphatase (A.J. Ganzhorn <IT>et al.</IT>). Screening of bacteria at high temperatures to select nucleoside antibiotics producers (T. Utagawa). Posters. Passive and active screening of D-hydantoinase-producing microorganisms (A. Morin, D. Leblanc). Selection and study of a <IT>Candida molischiana</IT> mutant derepressed for & bgr;-glucosidase production: application to flavor development of wines and fruit juices (Y. Gueguen <IT>et al.</IT>). Characterization of some isoprenoid-biosynthetic enzymes from plant cell cultures (R. van der Heijden <IT>et al</IT>.). Isolation, partial purification and characterization of a novel cyclic dipeptidase (D.P. Pantaleone <IT>et al.</IT>). Screening cultures using solid state fermentation (S. Suryanarayan <IT>et al.</IT>). Screening for polysaccharide-degrading micro-organisms (H.J. Ruijssenaars <IT>et al.</IT>). Isolation of a chitosan degrading fungus, <IT>Penicillium spinulosum, </IT> and chitosanase production by the isolate (Ö. Ak <IT>et al.</IT>). Author Index.

Includes bibliographical references and index.

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