Loomis's Essentials of Toxicology is an introductory text on the science of harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved; the general properties of chemicals and biologic systems as they influence the occurrence of detrimental biologic effects; the methods used to demonstrate these effects; and the basis for clinical diagnosis and therapy of harmful effects of chemicals on humans. Individual examples are used to demonstrate each of the principles under discussion. This text is an invaluable resource for toxicologists as well as a comprehensive introduction to the topic for graduate and advanced undergraduate students in toxicology and public health. Key Features * The "classic textbook" in toxicology * Completely revised and updated * Includes both principles and methods * Requires minimal background in chemistry and biology.

Introduction, Scope and Principles. -- Numbers in Toxicology. -- Biologic Factors that Influence Toxicity. -- Influence of Route of Administration on Systemic Toxicity. -- Genetic Factors that Influence Toxicity. -- Classifications of Harmful Effects of Chemicals. -- Normal Toxic Effects of Chemicals. -- Normal Toxic Effects of Chemicals. -- Abnormal Response to Chemicals. -- The Basis of Selective Toxicity. -- The Basis of Antidotal Therapy. -- Principles of Biological Tests for Toxicity. -- Toxicologic Testing Methods. -- Clinical Toxicology. -- Information Sources in Toxicology. -- Subject Index.

Includes bibliographical references and index.

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