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Membrane biogenesis and protein targeting / editors, Walter Neupert and Roland Lill.

Contributor(s): Series: New comprehensive biochemistry ; v. 22.1992Description: 1 online resource (xx, 343 pages) : illustrationsContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9780080860824
  • 0080860826
  • 1281754730
  • 9781281754738
Subject(s): Genre/Form: Additional physical formats: Print version:: Membrane biogenesis and protein targeting.LOC classification:
  • QD415 .N48 vol. 22 QP552.M44
NLM classification:
  • W1
  • QU 55
Online resources:
Contents:
Where are we in the exploration of Escherichia coli translocation pathways? / Bill Wickner -- Components involved in bacterial protein translocation / Chris Harris and Phang C. Tai -- Molecular characterization of Sec proteins comprising the protein secretory machinery of Escherichia coli / Shoji Mizushima, Hajime Tokuda and Shin-ichi Matsuyama -- Distinct steps in the insertion pathway of bacteriophage coat proteins / Andreas Kuhn and Dorothee Troschel -- Steps in the assembly of a cytoplasmic membrane protein: the MalF component of the maltose transport complex / Beth Traxler and Jon Beckwith -- Structural characteristics of presecretory proteins: their implication as to translocation competency / Shoji Mizushima [and others] -- Sequence determinants of membrane protein topology / Gumar von Heijne -- Lipid involvement in protein translocation / B. de Kruiff [and others] -- Membrane protein insertion into the endoplasmic reticulum: signals, machinery and mechanisms / Stephen High and Bernhard Dobberstein.
(cont) Translocation of proteins through the endoplasmic reticulum membrane: investigation of their molecular environment by cross-linking / Enno Hartmann and Tom A. Rapoport -- Role of GTP in protein targeting to the endoplasmic reticulum / Stephen C. Ogg [and others] -- Mechanism and regulation of import and degradation of cystolic proteins in the lysosome/vacuole / Hui-Ling Chiang and Randy Schekman -- Sorting of soluble and integral membrane proteins to the yeast vacuole / Christopher K. Raymond [and others] -- Defining components required for peroxisome assembly in Saccharomyces cerevisiae / Jorg Hohfeld [and others] -- Structure and assembly of peroxisomal membrane proteins / Joel M. Goodman, Lisa J. Garrard and Mark T. McCammon -- Mechanisms of transport of proteins into microbodies / Suresh Subramani -- Lessons for peroxisome biogenesis from fluorescence analyses of Zellweger syndrome fibroblasts / Paul B. Lazarow, Hugo W. Moser and Manuel J. Santos -- Mitochondrial protein import machinery of Saccharomyces cerevisiae / Victoria Hines.
(cont) Protein insertion into mitochondrial outer and inner membranes via the stop-transfer sorting pathway / Gordon C. Shore, Douglas G. Millar and Jian-Ming Li -- General and exceptional pathways of protein import into sub-mitochondrial compartments / Roland Lill [and others] -- Targeting of proteins into and across the chloroplastic envelope / H.-M. Li, S.E. Perry and K. Keegstra -- Transport of proteins into the thylakoids of higher plant chloroplasts / Colin Robinson -- Comparison of two different protein translocation mechanisms into chloroplasts / Jurgen Soll [and others] -- DnaJ homologs and protein transport / Takao Kurihara and Pamela A. Silver -- Chaperonin-mediated protein folding / Arthur L. Horwich [and others].
Action note:
  • digitized 2010 HathiTrust Digital Library committed to preserve
Summary: This book provides a comprehensive overview of recent developments in the fast moving field of protein transport across and into intracellular membranes. The soluble and membrane-bound components assisting in these processes are introduced, and their functions described. Besides a detailed analysis of protein translocation across the bacterial plasma membrane, the mechanisms of protein targeting within the eukaryotic cell are discussed with special focus on the transport of proteins to the endoplasmic reticulum, vacuoles, peroxisomes, mitochondria, and chloroplasts. Providing stimulating hypot.
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Includes bibliographical references and index.

Where are we in the exploration of Escherichia coli translocation pathways? / Bill Wickner -- Components involved in bacterial protein translocation / Chris Harris and Phang C. Tai -- Molecular characterization of Sec proteins comprising the protein secretory machinery of Escherichia coli / Shoji Mizushima, Hajime Tokuda and Shin-ichi Matsuyama -- Distinct steps in the insertion pathway of bacteriophage coat proteins / Andreas Kuhn and Dorothee Troschel -- Steps in the assembly of a cytoplasmic membrane protein: the MalF component of the maltose transport complex / Beth Traxler and Jon Beckwith -- Structural characteristics of presecretory proteins: their implication as to translocation competency / Shoji Mizushima [and others] -- Sequence determinants of membrane protein topology / Gumar von Heijne -- Lipid involvement in protein translocation / B. de Kruiff [and others] -- Membrane protein insertion into the endoplasmic reticulum: signals, machinery and mechanisms / Stephen High and Bernhard Dobberstein.

(cont) Translocation of proteins through the endoplasmic reticulum membrane: investigation of their molecular environment by cross-linking / Enno Hartmann and Tom A. Rapoport -- Role of GTP in protein targeting to the endoplasmic reticulum / Stephen C. Ogg [and others] -- Mechanism and regulation of import and degradation of cystolic proteins in the lysosome/vacuole / Hui-Ling Chiang and Randy Schekman -- Sorting of soluble and integral membrane proteins to the yeast vacuole / Christopher K. Raymond [and others] -- Defining components required for peroxisome assembly in Saccharomyces cerevisiae / Jorg Hohfeld [and others] -- Structure and assembly of peroxisomal membrane proteins / Joel M. Goodman, Lisa J. Garrard and Mark T. McCammon -- Mechanisms of transport of proteins into microbodies / Suresh Subramani -- Lessons for peroxisome biogenesis from fluorescence analyses of Zellweger syndrome fibroblasts / Paul B. Lazarow, Hugo W. Moser and Manuel J. Santos -- Mitochondrial protein import machinery of Saccharomyces cerevisiae / Victoria Hines.

(cont) Protein insertion into mitochondrial outer and inner membranes via the stop-transfer sorting pathway / Gordon C. Shore, Douglas G. Millar and Jian-Ming Li -- General and exceptional pathways of protein import into sub-mitochondrial compartments / Roland Lill [and others] -- Targeting of proteins into and across the chloroplastic envelope / H.-M. Li, S.E. Perry and K. Keegstra -- Transport of proteins into the thylakoids of higher plant chloroplasts / Colin Robinson -- Comparison of two different protein translocation mechanisms into chloroplasts / Jurgen Soll [and others] -- DnaJ homologs and protein transport / Takao Kurihara and Pamela A. Silver -- Chaperonin-mediated protein folding / Arthur L. Horwich [and others].

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This book provides a comprehensive overview of recent developments in the fast moving field of protein transport across and into intracellular membranes. The soluble and membrane-bound components assisting in these processes are introduced, and their functions described. Besides a detailed analysis of protein translocation across the bacterial plasma membrane, the mechanisms of protein targeting within the eukaryotic cell are discussed with special focus on the transport of proteins to the endoplasmic reticulum, vacuoles, peroxisomes, mitochondria, and chloroplasts. Providing stimulating hypot.

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