Includes bibliographical references and index.

Historical Evolution of Pain Concepts --History of Ion Channels in the Pain Sensory System -- The Nociceptive Membrane: Historical Overview -- TRPV1: A Polymodal Sensor in the Nociceptor Terminal -- Nociceptive Signals to TRPV1 and its Clinical Potential -- Gating, Sensitization, and Desensitization of TRPV1 -- TRP Channels as Thermosensors -- Acid Sensing Ionic Channels -- P2X Receptors in Sensory Neurons -- Voltage-Gated Sodium Channels and Neuropathic Pain -- Voltage-Gated Potassium Channels in Sensory Neurons -- Two-Pore Domain Potassium Channels in Sensory Transduction -- Finding Sensory Neuron Mechanotransduction Components -- Functional Diversity of Voltage-Dependent Ca2+ Channels in Nociception: Recent Progress in Genetic Studies -- Expression Patterns and Histological Aspects of TRP Channels in Sensory Neurons.

Membranes are essential cellular organelles. They not only define cells and other organelles, but also are critical in the cell function by selectively regulating the passage of molecules by acting as a matrix for other signaling molecules, and as conduits of information transfer between the external environment and the cell interior. This series was originally added in 1970 and has since provided a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology.

Print version record.

Elsevier ScienceDirect All Books