Completely revised to reflect the developments in this fast-changing field, this new edition features 35 % new content. It retains the interdisciplinary approach that elegantly combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. It also covers recent advances in preparative chromatographic processes for the separation of "smaller" molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants. The increase in biopharmaceutical substances is reflected by new and revised chapters.

Introduction / Henner Schmidt-Traub, Reinhard Ditz -- Fundamentals and general terminology / Andreas Seidel-Morgenstern, Michael Schulte, Achim Epping -- Stationary phases and chromatographic systems / Michael Schulte, Matthias Jöhnck, Romas Skudas, Klaus K Unger, Cedric du Fresne von Hohenesche, Wolfgang Wewers, Jules Dingenen, Joachim Kinkel -- Chromatography equipment: engineering and operation / Abdelaziz Toumi, Jules Dingenen, Joel Genolet, Olivier Ludemann-Hombourger, Andre Kiesewetter, Martin Krahe, Michele Morelli, Henner Schmidt-Traub, Andreas Stein, Eric Valery -- Process concepts / Malte Kaspereit, Michael Schulte, Klaus Wekenborg, Wolfgang Wewers -- Modeling and model parameters / Andreas Seidel-Morgenstern, Henner Schmidt-Traub, Mirko Michel, Achim Epping, Andreas Jupke -- Model-based design, optimization, and control / Henner Schmidt-Traub, Malte Kaspereit, Sebastian Engell, Arthur Susanto, Achim Epping, Andreas Jupke -- Appendix A: data of test systems -- Index.

Includes bibliographical references and index.

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