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Front Cover; The Cholinergic Synapse; Copyright Page; Contents; Preface; List of contributors; Abbreviations; Part I: Ultrastructure of Cholinergic Junctions; Synthesis of Acetylcholine; Chapter 1. The ultrastructure of autonomic cholinergic nerves and junctions; Chapter 2. The importance of axonal transport and endoplasmic reticulum in the function of cholinergic synapse in normal and pathological conditions; Chapter 3. Recent progress in the biochemistry of choline acetyltransferase; Chapter 4. Immunohistochemistry of choline acetyltransferase.

Chapter 5. Sodium-dependent high affinity choline uptakeChapter 6. Relationship of choline uptake to acetylcholine synthesis and release; Chapter 7. Choline uptake and metabolism by nerve cell cultures; Chapter 8. Regulation of acetylcholine synthesis in cholinergic nerve terminals; Chapter 9. Cholinergic false transmitters; Part II: Storage and Release of Acetylcholine; Chapter 10. On the mechanism of acetylcholine release; Chapter 11. Vesicular heterogeneity and turnover of acetylcholine and ATP in cholinergic synaptic vesicles.

Chapter 12. Role of vesicle recycling in vesicular storage and release of acetylcholine in Torpedo electroplaque synapsesChapter 13. Vesicular storage and release of cholinergic false transmitters; Chapter 14. Facilitation, augmentation, and potentiation of transmitter release; Chapter 15. The regulatory role of membrane Na+-K+ -ATPase in nonquantal release of transmitter at the neuromuscular junction; Chapter 16. Stimulation of cholinergic synaptosomes isolated from Torpedo electric organ; Chapter 17. Dual effect of noradrenaline on cholinergic transmission in guinea-pig ileum.

Part III: Postsynaptic Action of Acetylcholine: ElectrophysiologyChapter 18. Drug-receptor interaction at the frog neuromuscular junction; Chapter 19. The time course of postsynaptic currents in fast and slow junctions and its alteration by cholinesterase inhibition; Chapter 20. Activation of acetylcholine receptors in mammalian sympathetic ganglion neurones; Chapter 21. Acetylcholine as an excitatory and inhibitory transmitter in the mammalian central nervous system; Chapter 22. Studies on a false transmitter at the neuromuscular junction.

Part IV: Postsynaptic Action of Acetylcholine: BiochemistryChapter 23. The nicotinic acetylcholine receptor from Torpedo electroplax; Chapter 24. Acetylcholine receptor of Limnaea stagnalis neurones. Study of the active site functional groups; Chapter 25. Biochemical characterization of muscarinic receptors: multiplicity of binding components; Chapter 26. Cholinesterases of the motor end-plate of the rat diaphragm; Part V: Development of Cholinergic Synapses; Neurotrophic Regulation; Intercelluar Relations; Chapter 27. The life history of acetylcholine receptors.

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