Includes bibliographical references and index.

Basal bodies: platforms for building cilia / Wallace F. Marshall -- Intraflagellar transport (IFT): role in ciliary assembly, resorption and signalling / Lotte B. Pedersen and Joel L. Rosenbaum -- How did the cilium evolve? / Peter Satir, David R. Mitchell, and Gáspár Jékely -- Ciliary tubulin and its post-translational modifications / Jacek Gaertig and Dorota Wloga -- Targeting protein to the ciliary membrane / Gregory J. Pazour and Robert A. Bloodgood -- Cilia: multifunctional organelles at the center of the vertebrate left-right asymmetry / Basudha Basu and Martina Brueckner -- Ciliary function and Wnt signal modulation / Jantje M. Gerdes and Nicholas Katsanis -- Primary cilia in planar cell polarity regulation of the inner ear / Chonnettia Jones and Ping Chen -- The primary cilium: at the crossroads of mammalian hedgehog signaling / Sunny Y. Wong and Jeremy F. Reiter -- The primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair / Søren T. Christensen [and others] -- Cilia involvement in patterning and maintenance of the skeleton / Courtney J. Haycraft and Rosa Serra -- Olfactory cilia: our direct neuronal connection to the external world / Dyke P. McEwen, Paul M. Jenkins, and Jeffrey R. Martens -- Ciliary dysfunction in developmental abnormalities and diseases / Neeraj Sharma, Nicolas F. Berberi, and Bradley K. Yoder.

Cilia - the tiny hair-like structures on the surface of cells - have been identified as playing a role in a variety of disease and developmental disorders. This volume presents the fresh findings in cilia research and thought on the role of cilia in disease and developmental abnormalities.

Elsevier ScienceDirect All Books