Growth in knowledge about the microcirculation has been explosive with the field becoming fragmented into numerous sub-disciplines and subspecialties. This volume pulls all of the critical information into one volume eliminating the need to search through numerous books and journals which can be exhaustive and demanding. It provides cardiovascular physiologists with an integrated, in-depth evaluation of the latest research developments and will aide in developing new pathways of research and scholarship. Key Features Meticulously edited and reviewed. Benefit: Provides investigators a unique tool to explore the significance of their findings in the context of other aspects of the microcirculation. In this way, the updated edition has a direct role in helping to develop new pathways of research and scholarship. Highlights the explosive growth in knowledge about the microcirculation including the biology of nitric oxide synthase (NOS), endothelial cell signaling, angiogenesis, cell adhesion molecules, lymphocyte trafficking, ion channels and receptors, and propagated vasomotor responses. Benefit: Microcirculatory biology has become fragmented into numerous sub-disciplines and subspecialties, and these reference reintegrates the information in one volume.

Includes bibliographical references and index.

Preface -- Introduction: Overview of the microcirculation / Paul C. Johnson -- pt. I: Principles of microvascular structure and function. Blood flow in microvascular networks / Axel R. Pries and Timothy W. Secomb ; Physiology and pathobiology of microvascular endothelium / Jordan S. Pober ; Biology of nitric oxide synthases / Ingrid Fleming ; Microcirculatory exchange function / Walter N. Durán, Fabiola A. Sánchez and Jerome W. Breslin -- Microlymphatic biology / David C. Zawieja, Pierre-Yves von der Weid and Anatoliy A. Gashev -- pt. II: Regulation of the microvascular blood flow. Local regulation of microvascular perfusion / Michael J. Davis, Michael A. Hill and Lih Kuo ; Receptor-mediated events in the microcirculation / Stephanie W. Watts, Nancy L. Kanagy, and Julian H. Lombard -- pt. III: Adaption of the vascular system. Angiogenesis / Mary E. Gerritsen -- pt. IV: Inflammatory and immune functions. The microcirculation in inflammation / Klaus Ley ; Lymphocyte trafficking / Avi N. Kogan and Ulrich H. von Andrian -- pt. V: Microcirculatory specialization in individual organs. The cerebral microcirculation / Ronald F. Tuma ; Regulation of coronary microvascular resistance in health and disease / Cuihua Zhang [and others] ; The renal microcirculation / L. Gabriel Navar [and others]. ; Gastrointestinal and liver microcirculations: roles in inflammation and immunity / Soichiro Miura, Paul Kubes and D. Neil Granger ; The pulmonary microcirculation / Jahar Bhattacharya, Michael Koval and Wolfgang M. Kuebler ; Microcirculation of the ocular fundus / Charles E. RIva and Leopold Schmetterer -- pt. VI: Microcirculation in health and disease. Sickle cell disease / Dhananjay K. Kaul ; Pathophysiology of primary hypertension / Robert M. Carey ; Microvascular consequences of obesity and diabetes / H. Glenn Bohlen.

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