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001 978-0-387-28980-9
003 DE-He213
005 20160614135112.0
007 cr nn 008mamaa
008 100301s2005 xxu| s |||| 0|eng d
020 _a9780387289809
_9978-0-387-28980-9
024 7 _a10.1007/0-387-28980-1
_2doi
049 _aAlfaisal Main Library
050 4 _aQA273.A1-274.9
050 4 _aQA274-274.9
072 7 _aPBT
_2bicssc
072 7 _aPBWL
_2bicssc
072 7 _aMAT029000
_2bisacsh
082 0 4 _a519.2
_223
100 1 _aMolenberghs, Geert.
_eauthor.
245 1 0 _aModels for Discrete Longitudinal Data
_h[electronic resource] /
_cby Geert Molenberghs, Geert Verbeke.
264 1 _aNew York, NY :
_bSpringer New York,
_c2005.
300 _aXXII, 687 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Series in Statistics,
_x0172-7397
505 0 _aMotivating Studies -- Generalized Linear Models -- Linear Mixed Models for Gaussian Longitudinal Data -- Model Families -- The Strength of Marginal Models -- Likelihood-based Marginal Models -- Generalized Estimating Equations -- Pseudo-Likelihood -- Fitting Marginal Models with SAS -- Conditional Models -- Pseudo-Likehood -- From Subject-specific to Random-effects Models -- The Generalized Linear Mixed Model (GLMM) -- Fitting Generalized Linear Mixed Models with SAS -- Marginal versus Random-effects Models -- The Analgesic Trial -- Ordinal Data -- The Epilepsy Data -- Non-linear Models -- Pseudo-Likelihood for a Hierarchical Model -- Random-effects Models with Serial Correlation -- Non-Gaussian Random Effects -- Joint Continuous and Discrete Responses -- High-dimensional Joint Models -- Missing Data Concepts -- Simple Methods, Direct Likelihood, and Weighted Generalized Estimating Equations -- Multiple Imputation and the Expectation-Maximization Algorithm -- Selection Models -- Pattern-mixture Models -- Sensitivity Analysis -- Incomplete Data and SAS.
520 _aThis book provides a comprehensive treatment on modeling approaches for non-Gaussian repeated measures, possibly subject to incompleteness. The authors begin with models for the full marginal distribution of the outcome vector. This allows model fitting to be based on maximum likelihood principles, immediately implying inferential tools for all parameters in the models. At the same time, they formulate computationally less complex alternatives, including generalized estimating equations and pseudo-likelihood methods. They then briefly introduce conditional models and move on to the random-effects family, encompassing the beta-binomial model, the probit model and, in particular the generalized linear mixed model. Several frequently used procedures for model fitting are discussed and differences between marginal models and random-effects models are given attention The authors consider a variety of extensions, such as models for multivariate longitudinal measurements, random-effects models with serial correlation, and mixed models with non-Gaussian random effects. They sketch the general principles for how to deal with the commonly encountered issue of incomplete longitudinal data. The authors critique frequently used methods and propose flexible and broadly valid methods instead, and conclude with key concepts of sensitivity analysis. Without putting too much emphasis on software, the book shows how the different approaches can be implemented within the SAS software package. The text is organized so the reader can skip the software-oriented chapters and sections without breaking the logical flow. Geert Molenberghs is Professor of Biostatistics at the Universiteit Hasselt in Belgium and has published methodological work on surrogate markers in clinical trials, categorical data, longitudinal data analysis, and the analysis of non-response in clinical and epidemiological studies. He served as Joint Editor for Applied Statistics (2001–2004) and as Associate Editor for several journals, including Biometrics and Biostatistics. He was President of the International Biometric Society (2004–2005). He was elected Fellow of the American Statistical Association and received the Guy Medal in Bronze from the Royal Statistical Society. Geert Verbeke is Professor of Biostatistics at the Biostatistical Centre of the Katholieke Universiteit Leuven in Belgium. He has published a number of methodological articles on various aspects of models for longitudinal data analyses, with particular emphasis on mixed models. Geert Verbeke is Past President of the Belgian Region of the International Biometric Society, International Program Chair for the International Biometric Conference in Montreal (2006), and Joint Editor of the Journal of the Royal Statistical Society, Series A (2005–2008). He has served as Associate Editor for several journals including Biometrics and Applied Statistics. The authors also wrote a monograph on linear mixed models for longitudinal data (Springer, 2000) and received the American Statistical Association's Excellence in Continuing Education Award, based on short courses on longitudinal and incomplete data at the Joint Statistical Meetings of 2002 and 2004. .
650 0 _aMathematics.
650 0 _aProbabilities.
650 0 _aStatistics.
650 1 4 _aMathematics.
650 2 4 _aProbability Theory and Stochastic Processes.
650 2 4 _aStatistical Theory and Methods.
650 2 4 _aStatistics for Life Sciences, Medicine, Health Sciences.
655 7 _aElectronic books.
_2local
700 1 _aVerbeke, Geert.
_eauthor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387251448
830 0 _aSpringer Series in Statistics,
_x0172-7397
856 4 0 _uhttp://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/0-387-28980-1
912 _aZDB-2-SMA
942 _2lcc
_cEBOOKS
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