000 04320nam a22005415i 4500
001 978-0-387-77944-7
003 DE-He213
005 20160614140137.0
007 cr nn 008mamaa
008 100301s2008 xxu| s |||| 0|eng d
020 _a9780387779447
_9978-0-387-77944-7
024 7 _a10.1007/978-0-387-77944-7
_2doi
049 _aAlfaisal Main Library
050 4 _aQR1-502
072 7 _aPSG
_2bicssc
072 7 _aSCI045000
_2bisacsh
082 0 4 _a579
_223
245 1 0 _aAcinetobacter Biology and Pathogenesis
_h[electronic resource] /
_cedited by Mauro Bendinelli, Herman Friedman, Eugénie Bergogne-Bérézin.
264 1 _aNew York, NY :
_bSpringer US,
_c2008.
300 _aXVI, 220 p. 17 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aInfectious Agents and Pathogenesis,
_x1075-1289
505 0 _aImportance of Acinetobacter spp. -- “Overview of the Microbial Characteristics, Taxonomy, and Epidemiology of Acinetobacter” -- Genome Organization, Mutation, and Gene Expression in Acinetobacter -- Molecular Epidemiology of Acinetobacter Species -- Typing Acinetobacter Strains: Applications and Methods -- Efflux Pumps in Acinetobacter baumannii -- Acinetobacter baumannii: Mechanisms of Resistance, Multiple ß-Lactamases -- Virulence Mechanisms of Acinetobacter -- Nosocomial and Community-acquired Acinetobacter Infections -- Experimental Models of Acinetobacter Infection -- Antimicrobial Resistance and Therapeutic Alternatives -- US Army Experience with Acinetobacter in Operation Iraqi Freedom -- Perspectives.
520 _aThere is currently increasing interest concerning the biology and disease caused by Acinetobacter species. Such interest, however, developed relatively slowly because of the necessity to clarify the confusing taxonomy of these organisms. Much work was needed to identify various species as members of this genus, to recognize their epidemiologic profile, their pathogenic role and their increasing importance as multi-antibiotic resistant organisms. In recent years improvement of genetic approaches, recognition of plasmids, integrons and chromosomal sources of resistance mechanisms aroused interest on the role of Acinetobacters in disease by many microbiologists and clinicians, especially internists and infectious disease specialists. In this regard, physicians are frequently confronted with extremely difficult therapeutic approaches for treatment and prevention of severe nosocomial infections due to multi antibiotic resistant Acinetobacter. Moreover, recent observations of community acquired infections have been reported, especially in patients with various risk factors such as immuno-deficiencies. Also, it is now becoming evident that Acinetobacter infections occur frequently in violent situations such as earthquake or war zones. The mechanisms of Acinetobacter virulence are becoming increasingly clear, providing new insights into their pathogenic role in community acquired infections. It is apparent the time is appropriate for detailed review of the increasing knowledge concerning important new information, both clinical and therapeutic, especially information concerning virulence, resistance mechanisms and typing of Acinetobacter spp. Many new findings are accumulating in almost an exponential manner since publication of previous books on this subject in 1991 and 1996.
650 0 _aLife sciences.
650 0 _aImmunology.
650 0 _aVirology.
650 0 _aMicrobiology.
650 1 4 _aLife Sciences.
650 2 4 _aMicrobiology.
650 2 4 _aImmunology.
650 2 4 _aVirology.
655 7 _aElectronic books.
_2local
700 1 _aBendinelli, Mauro.
_eeditor.
700 1 _aFriedman, Herman.
_eeditor.
700 1 _aBergogne-Bérézin, Eugénie.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387779430
830 0 _aInfectious Agents and Pathogenesis,
_x1075-1289
856 4 0 _uhttp://ezproxy.alfaisal.edu/login?url=http://dx.doi.org/10.1007/978-0-387-77944-7
912 _aZDB-2-SBL
942 _2lcc
_cEBOOKS
999 _c253278
_d253278